Calcium phosphate has been widely used in bone regeneration applications. Originalkalsium fosfat merupakan biomaterial yang sering diaplikasikan ke dalam defek tulang dengan tidak memberikan efek toksik pada jaringan sehat.The most commonly calcium are hydroxyapatite and β-tricalcium (β-TCP). β-TCP is one of the bioceramic materials that chemical structure β-Ca3(PO4)2. The use medicine dentistr...

Calcium carbonate-based bone substitutes derived from natural coral exoskeleton (aragonite) are resorbed and remodeled faster than calcium phosphate-based substitutes. However, species with structures appropriate for use as very limited. Therefore, it is important to evaluate potential of artificial carbonate ceramics a substitute. In this study, granules various porosities pore sizes were prep...

the bulk of the world's phosphate reserves is located in sedimentary horizons that contain appreciable amounts of carbonate. during beneficiation of phosphate rocks, huge amounts of oversize phosphate rocks are rejected from crushers. this reject also mostly contains low tricalcium phosphate and high carbonate content. in this study, experiments have been carried out to reduce/eliminate carbona...

INTRODUCTION: Composites of purified collagen and calcium phosphate salts have been widely used to produce osteoconductive scaffolds for fracture healing and spinal fusion. The effects of different calcium phosphate additives in a collagen scaffold was previously investigated in a rat model of ectopic bone formation induced by a mixture of bovine bone derived growth factors. It was found that o...

The aim of this study was to evaluate the therapeutic efficacy of biomimetic zinc-containing tricalcium phosphate (ZnTCP) produced by hydrothermally converting calcium carbonate exoskeletons from foraminifera, in the treatment of osteoporotic mice. X-Ray powder diffraction showed crystallographic structures matching JCPDS profile for tricalcium phosphate. Mass spectroscopy used to calculate tot...

The biological behavior of a new bioactive material composed of calcium-deficient hydroxyapatite, octacalcium phosphate, and β-tricalcium phosphate was investigated by in vitro indirect and direct cytotoxicity, cell adhesion and proliferation tests, and by in vivo subcutaneous and bone implantation in rats. The results of the in vitro studies showed that the material is biocompatible and no cyt...