Cancer is predominantly a somatic disease. A mutant allele present in a cancer cell genome is considered somatic when it's absent in the paired normal genome along with public SNP databases. The current build of dbSNP, the most comprehensive public SNP database, however inadequately represents several non-European Caucasian populations, posing a limitation in cancer genomic analyses of data fro...

INTRODUCTION The trapeziometacarpal (TMC) joint of the human thumb is the second most common joint in the hand affected by osteoarthritis. TMC arthroplasty is a common procedure used to alleviate symptoms. No randomized controlled trials have been published on the efficacy of different post-operative orthotic regimes. METHOD Fifty six participants who underwent TMC arthroplasty were allocated...

Thin film nanocomposite (TFN) membranes containing MCM-41 silica nanoparticles (NPs) were synthesized by the interfacial polymerization (IP) process. An m-phenylenediamine (MPD) aqueous solution and an organic phase with trimesoyl chloride (TMC) dissolved in isooctane were used in the IP reaction, occurring on a nanoporous polysulfone (PSU) support layer. Isooctane was introduced as the organic...

INTRODUCTION There is a paucity of data evaluating whether a multidisciplinary conference coordinating surgery, chemotherapy and radiation therapy translates into better patient care. This article compares the experiences of patients with lung cancer before and after the formation of a prospective, multidisciplinary thoracic malignancy care conference (TMC). METHODS The records of patients wi...

OBJECTIVE The purpose of this report is to describe the management of a patient with advanced trapeziometacarpal (TMC) osteoarthritis (OA) using mobilization with movement technique in combination with kinesiology tape to decrease pain and improve range of motion. CLINICAL FEATURES A 52-year-old female seamstress (a career of 35 years' duration) presented to a physiotherapy clinic with pain i...

Carcinomas of the breast with prominent lymphoplasmacytic background are commonly encountered in cytology. The aim of this study was to assess the prevalence of different types of carcinomas that share this common feature, identify possible distinguishing cytologic features, and evaluate the diagnostic pitfalls in this group of tumors. Eighteen fine-needle aspirations (FNAs) of breast carcinoma...

The topic of the paper concerns the implementation and use of standards. The standards which are in focus in the paper include conceptual models and descriptions of the functionality and information exchange which should be provided in order to deliver ICT-services. This implies that these conceptual standards are specifications and guidelines for the information systems used to provide ICT-ser...

Carboxyls are inherent functional groups of thin-film composite polyamide nanofiltration (NF) membranes, which may play a role in membrane performance and fouling. Their surface presence is attributed to incomplete reaction of acyl chloride monomers during the membrane active layer synthesis by interfacial polymerization. In order to unravel the effect of carboxyl group density on organic fouli...

Increasing traffic, especially in urban areas, leads to more and more infrastructural bottlenecks and congestion inside transportation networks. The aim is therefore to use existing transport networks as efficiently as possible. Live traffic and incident reports from the Traffic Message Channel (TMC) are an important source of information to provide further services in the context of a dynamic ...

A positive effect of intra-articular platelet-rich plasma (PRP) injection has been discussed for osteoarthritic joint conditions in the last years. The purpose of this study was to evaluate PRP injection into the trapeziometacarpal (TMC) joint. We report about ten patients with TMC joint osteoarthritis (OA) that were treated with 2 intra-articular PRP injections 4 weeks apart. PRP was produced ...