The Tycoon Store Protocol (TSP) speciies a clean interface between the frontend and the backend of fully integrated persistent environments. In contrast to high-level relational or object-oriented database languages, TSP is based on a low level, untyped, but highly exible tagged store model that is particularly well-suited for the implementation of higher-order persistent polymorphic languages....

In the classical Travelling Salesman Problem (TSP), the objective function sums the costs for travelling from one city to the next city along the tour. In the q-stripe TSP with [Formula: see text], the objective function sums the costs for travelling from one city to each of the next q cities in the tour. The resulting q-stripe TSP generalizes the TSP and forms a special case of the quadratic a...

The Tycoon Store Protocol (TSP) specifies a clean interface between the frontend and the backend of fully integrated persistent environments. In contrast to high-level relational or object-oriented database languages, TSP is based on a low level, untyped, but highly flexible tagged store model that is particularly well-suited for the implementation of higher-order persistent polymorphic languag...

The Traveling Salesman Problem is one of the best studied NP-hard problems in combinatorial optimization. Powerful methods have been developed over the last 60 years to find optimum solutions to large TSP instances. The largest TSP instance so far that has been solved optimally has 85,900 vertices. Its solution required more than 136 years of total CPU time using the branch-and-cut based Concor...

The quadratic travelling salesman problem (QTSP) is to find a least cost Hamiltonian cycle in an edge-weighted graph. We define a restricted version of QTSP, the kneighbour TSP (TSP(k)), and give a linear time algorithm to solve TSP(k) on a Halin graph for k ≤ 3. This algorithm can be extended to solve TSP (k) on any fully reducible class of graphs for any fixed k in polynomial time. This resul...

Since the discovery of thrombospondin (TSP)-1 thirty years ago,1 this matricellular (regulating cell–matrix interaction) protein has been a focal point for attention of cardiovascular biologists. Initial studies of TSP-1 emphasized its role as a major constituent of platelet -granules and its involvement in platelet aggregation and thrombosis. However, it soon became clear that other cell types...

Since the discovery of thrombospondin (TSP)-1 thirty years ago,1 this matricellular (regulating cell–matrix interaction) protein has been a focal point for attention of cardiovascular biologists. Initial studies of TSP-1 emphasized its role as a major constituent of platelet -granules and its involvement in platelet aggregation and thrombosis. However, it soon became clear that other cell types...

ABSTRACT. Linear, nonlinear optical properties, photon buildup factors, and neutron shielding capability of glasses with chemical composition (65-x)B2O3-10Sb2O3-25Li2O-xBi2O3, where x = 0 (BSLB0) – 20 (BSLB20) mol% steps 4 were examined. Molar refractivity (Rmolar) molar polarizability (αmolar) increased as Bi2O3 content increase in the examined BSLB-glasses. The values metallization criterion ...

ANG II induces secretion and activation of transforming growth factor-beta (TGF-beta) by glomerular mesangial cells. However, the mechanisms that operate this are unclear. Thrombospondin-1 (TSP-1), which is produced by mesangial cells in damaged glomeruli, is one of several molecules known to activate the latent TGF-beta1 complex. Therefore, we examined whether the ANG II-induced activation of ...

OBJECTIVE Thrombospondin-1 (TSP-1), a trimeric glycoprotein, is involved in cell-matrix interactions of various tissues, particularly in cartilage. Biochemical analyses show expression of TSP-1 in human cartilage, but its cellular source as well as the presence of its main surface receptors CD36 and CD51 in normal and osteoarthritic cartilage remain unknown. Therefore, to localise TSP-1 and its...