نتایج جستجو برای: tubular support
تعداد نتایج: 686164 فیلتر نتایج به سال:
Three cases of epididymal adenomatoid tumor are presented. The adenoid compositions of the tumors lined by epithelial cells showed a canalicular pattern with large vascular spaces, tubular pattern with glandlike regions or plexiform pattern with connective tissue strands. Immunohistochemistry demonstrated positive cytoplasmic staining for keratin, but negative for carcinoembryonic antigen and f...
Lysosomes are classically viewed as vesicular structures to which cargos are delivered for degradation. Here, we identify a network of dynamic, tubular lysosomes that extends throughout Drosophila muscle, in vivo. Live imaging reveals that autophagosomes merge with tubular lysosomes and that lysosomal membranes undergo extension, retraction, fusion and fission. The dynamics and integrity of thi...
BACKGROUND Tubular repair upon injury involves regeneration from either surviving tubular epithelial cells or from their surviving local progenitor cells; hence, compound screening with cell lines may be inadequate. Here, we demonstrate that the renal cell isolation procedure and subsequent outgrowth of tubular cells can mimic the renal injury phase and tubular cell regeneration from whichever ...
Acute kidney injury (AKI) is a potentially fatal syndrome characterized by a rapid decline in kidney function caused by ischemic or toxic injury to renal tubular cells. The widely used chemotherapy drug cisplatin accumulates preferentially in the renal tubular cells and is a frequent cause of drug-induced AKI. During the development of AKI the quiescent tubular cells reenter the cell cycle. Str...
MARSH, DONALD J. Solute and water flows in thin limbs of Henle’s loop in the hamster kidney. Am. J. Physiol. 218(3) : 824433 1. 1970. -Collections were made from two sites in single thin limbs on the surface of the exposed hamster papilla. There was no change of the inulin TF/P along the first millimeter of thin ascending limb, a result that rules out hypotheses of hypertonic urine formation re...
Knock-Down of CD44 Regulates Endothelial Cell Differentiation via NFκB-Mediated Chemokine Production
A striking feature of microvascular endothelial cells is their capacity to fuse and differentiate into tubular structures when grown in three-dimensional (3D) extracellular matrices, in collagen or Matrigel, mimicking the in vivo blood vessel formation. In this study we demonstrate that human telomerase-immortalised foreskin microvascular endothelial (TIME) cells express high levels of the hyal...
MARSH, DONALD J. Solute and water flows in thin limbs of Henle’s loop in the hamster kidney. Am. J. Physiol. 218(3) : 824433 1. 1970. -Collections were made from two sites in single thin limbs on the surface of the exposed hamster papilla. There was no change of the inulin TF/P along the first millimeter of thin ascending limb, a result that rules out hypotheses of hypertonic urine formation re...
In AKI, dying renal cells release intracellular molecules that stimulate immune cells to secrete proinflammatory cytokines, which trigger leukocyte recruitment and renal inflammation. Whether the release of histones, specifically, from dying cells contributes to the inflammation of AKI is unknown. In this study, we found that dying tubular epithelial cells released histones into the extracellul...
Chinese-herb nephropathy (CHN) is a rapidly progressive renal fibrosis associated with the intake of a Chinese herb (Aristolochia fangchi) containing nephrotoxic and carcinogenic aristolochic acids (AA). This study attempted to reproduce the main features of human CHN (renal failure, tubular atrophy, and interstitial fibrosis) in a rat model similar to that of cyclosporin-induced nephropathy. S...
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