Background: Bax and Bcl-2 are the major members of Bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. Therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. Methods: In this study, the relative level of mRNA expression of Bax and Bcl-2 genes was deter...

this retrospective study was conducted to determine the prevalence of nasopharyngeal angiofibroma according to age, stage, clinical signs and average blood transfusion during surgery in educational hospitals affiliated to isfahan university of medical sciences. background: this retrospective study was conducted on 250 records of patients suffering from angiofibroma and hospitalized from 1988 to...

background: triple-negative breast cancers (tnbc) have a more aggressive course and are associated with poorer prognosis in comparison with other subtypes of breast cancer. one of the most common subtypes of tnbc is basal-like. the aim of this study was to investigate clinicopathological characteristics and clinical course of tnbc in iranian women and compare them with other studies. subjects a...

introduction: breast cancer is the most common of all malignant neoplasms in women worldwide. this study aims to demonstrate certain biological, clinical and pathological characteristics of patients treated at the university hospital oncology unit. methods: a descriptive study was conducted during a period of 2 years, from october 2003 through september of 2005 in kermanshah, iran. 555 patients...