Candida species are increasingly important nosocomial pathogens in critically ill children. A 2.3-fold increase in the rate of nosocomial candidemia at our 200-bed tertiary care children's hospital prompted a study to identify risk factors for this infection. Twenty-six cases were identified between 1992 and 1993, representing 21% of all nosocomial bloodstream infections. Candida albicans was t...

Central venous catheters (CVCs) are a common adjunct to hemophilia therapy, but the risk of CVC-related deep venous thrombosis (DVT) in hemophiliacs is not well defined. In a previous study, 13 patients with CVCs had no radiographic evidence of DVT. However, recent abstracts and case studies demonstrate that DVT does occur. Therefore, this study sought to determine the frequency of DVT in child...

Introduction: Catheter-related infection (CRI) is one of the most common vascular access complications in dialysis catheter-related procedures. However, repeated chronic infected ulcer that leads to suspected malignancy a tunneled catheter (TDC) insertion site and its risk factor have not been reported. Case description: A 37 years-old woman presented with exudative right breast at entry cathet...

background: central venous catheters (cvcs) have been used widely in clinics. these catheters are also recommended for children and infants receiving chemotherapy and total parenteral nutrition (tpn) and etc. in this paper, we present migrated fractured control line of the heart of a girl. case presentation: a 2.5 year old girl with migrated of the fractured central line into the heart. in the ...

1. MCINTYRE CW, HULME LJ, TAAL M, FLUCK RJ: Locking of tunneled hemodialysis catheters with gentamicin and heparin. Kidney Int 66:801–805, 2004 2. DOGRA GK, HERSON H, HUTCHISON B, et al: Prevention of tunnelled haemodialysis catheter-related infections using catheter-restricted filling of gentamicin and citrate: A randomised control study. J Am Soc Nephrol 13:2133–2139, 2002 3. SAXENA AK, PANHO...

BACKGROUND Acute kidney injury requiring renal replacement therapy (AKI-RRT) is associated with high morbidity, mortality and resource utilization. The type of vascular access placed for AKI-RRT is an important decision, for which there is a lack of evidence-based guidelines. METHODS We conducted a prospective cohort study over a 16-month period with 154 patients initiated on AKI-RRT via eith...

BACKGROUND Central venous catheter-related infections (CVCIs) in patients on maintenance hemodialysis (HD) have been documented due to unsafe/unsterile manipulations by nurses during HD machine deconnection and reconnection. Given the gravity of CVCIs in HD patients using catheter access, precise, safe installation of the device, and good nursing technique are crucial. AIM To assess and compa...