we report a spontaneous unilateral live tubal twin pregnancy in a patient with a history of previous ectopic pregnancy (ep) and tubal surgery. transvaginal ultrasound showed one pregnancy sac containing two fetal poles with cardiac activity, which appeared to be sited within the right adnexum. the right tubal ep was removed by salpingectomy. ultrasound findings of suspected adnexal mass and fre...

inflammatory bowel disease (ibd) frequently affects young patients of childbearing age. treatments for inflammatory bowel disease include immunosuppressive, cytotoxic and surgical therapies. azathioprine is frequently used to treat patients with steroid dependent ibd. we report the case of a patient with ulcerative colitis, treated with azathioprine prior to conception and during the subsequent...

INTRODUCTION Twin reversed arterial perfusion (TRAP) sequence is a rare complication of multiple pregnancy caused by defects in early embryogenesis. The pump twin supplies the acardiac recipient twin with blood, and although the pump twin is usually structurally normal, congenital anomalies have sometimes been reported. We report a unique case of twin reversed arterial perfusion sequence with a...

Definition: A complication of monozygotic twin pregnancies in which one fetus develops normally (pump twin) and the second twin (recipient twin) demonstrates cardiac mal development ranging from complete absence of heart tissue to some formation of rudimentary myocardia. Etiology: Probable reversal of circulation in the anomalous twin resulting from anastomosis of circulation between the twins ...

we present unusual retained remnants of hidden conjoined twin of possible abdominal pagus after 21 years who presented with abdomenpain and incidentally have found his forbidden conjoined twin. he presented for many years with a palpable epigastric mass, and recent abdominal pain, early satiety, nausea and vomiting. the mass was a like deformed fetus weighing 815 gr who was anencephalic and dep...

The basis of most twin studies is the ascertainment of twins, often through twin registries, and determination of zygosity. The current rate of twin births in many industrialized countries implies that in the near future around 3% or more of individuals will be a twin. Hence, there are and will be a lot of twins around and many of those will not participate in twin studies. However, if large po...

Twin pairs discordant for disease may help elucidate the epigenetic mechanisms and causal environmental factors in disease development and progression. To obtain the numbers of pairs, especially monozygotic (MZ) twin pairs, necessary for in-depth studies while also allowing for replication, twin studies worldwide need to pool their resources. The Discordant Twin (DISCOTWIN) consortium was estab...

The purpose was to compare the sella turcica morphology of individuals within pairs of monozygotic twins with normal karyotype and to analyze the similarity between the observed morphology and the morphology of non-twins at the same age with normal karyotype. Profile radiographs from 84 individuals of 42 twin pairs (18 male and 24 female pairs, aged 18-23 years) comprised the material. Sella tu...

The aim of this study was to compare different fetal growth curves in twin pregnancies with severe placental insufficiency. A retrospective cross-sectional analysis of 47 twin pregnancies with absent or reverse end diastolic flow in the umbilical artery of one fetus was performed. Pregnancies with major fetal abnormalities, twin-twin transfusion or three or more fetuses were not included. The e...

The objective of this review is to assess the evidence which supports the use of non-invasive prenatal diagnosis (NIPD) in twin pregnancies. Through the years, we have witnessed the technological developments in non-invasive prenatal diagnosis attained new heights, but those studies were usually limited in singleton pregnancies. As we known, twin pregnancies are at higher risk in both aneuploid...