according to the importance of careful review of crude oil market fluctuations on the iranian economy, in this paper a multivariate model of markov switching vector error correction model (have been used). variables such as real gross domestic product in industrial sector, real effective exchange rate, real governmental expenditure, real import, inflation rate and real crude oil price is used t...

In order to establish criteria for the serodiagnosis of foamy virus infections we investigated the extent to which sera from infected individuals of human and primate origin react with structural and non-structural virus proteins in immunoblot assays. Using lysates from infected cells as the source of virus antigen, antibodies were preferentially detected against the Gag proteins and the non-st...

Several days after unprotected sex, a 21-year-old male was referred with generalized edema and enlarged painless lymph nodes. Urinalysis showed specific gravity 1036, proteinuria 4+, nitrites negative, urine microscopy with 4–6 erythrocytes/high power field (HPF), 8–10 leucocytes/HPF and the presence of hyaline and granular casts. Urine culture was negative. Proteinuria was 4.6 g/24 h, serum cr...

Retroviral gene therapy offers immense potential to treat many genetic diseases and has already shown efficacy in clinical trials. However, retroviral vector mediated genotoxicity remains a major challenge and clinically relevant approaches to reduce integration near genes and proto-oncogenes are needed. Foamy retroviral vectors have several advantages over gammaretroviral and lentiviral vector...

We study voting games on binary issues, where voters hold an objective over the outcome of the collective decision and are allowed, before the vote takes place, to negotiate their voting strategy with the other participants. We analyse the voters’ rational behaviour in the resulting two-phase game, showing under what conditions undesirable equilibria can be removed and desirable ones sustained ...

We prove that under mild regularity assumptions on the initial data the two-phase classical Stefan problem admits a (unique) solution that is analytic in space and time.

Background An internal pilot study is the first part of a substantive RCT where trial parameters are examined and data contribute to the final analyses. This two-phase design provides an opportunity to review pre-agreed ‘progression criteria’ that determine whether the internal pilot should continue into the main trial. Selecting appropriate criteria is critical but little is known about this a...