Contact hypersensitivity (CH) to simple haptens and acute allograft rejection are generally regarded as T cell-mediated responses. However, at the present time, considerable controversy exists concerning the precise phenotype of the effector cells that are the proximate causes of inf lammation and tissue destruction. In transplantation immunity, the assumption of a decade a g o t h a t cytotoxi...

This study was performed to examine the possibility of Er:YAG laser for dentine hypersensitivity treatment using a novel laser probe; broom-type probe. The morphological change of dentinal tubules of bovine dentine plate after low power laser irradiation (5 or 10 mJ/ pulse, 10 pps) or boiling was observed by SEM. Fifty teeth from 13 patients aged 31–54 years with complaint of dentine hypersensi...

Hypersensitivity pneumonitis (HP) is a granulomatous interstitial lung disease caused by the inhalation of a variety of antigens and is characterized by a dramatic accumulation of inflammatory cells, including neutrophils, lymphocytes and macrophages, in the lung. The mechanisms implicated in the inflammatory cell recruitment observed in hypersensitivity pneumonitis are unknown. We examined the...

[Purpose] Auditory hypersensitivity has been widely reported in patients with autism spectrum disorders. However, the neurological background of auditory hypersensitivity is currently not clear. The present study examined the relationship between sympathetic nervous system responses and auditory hypersensitivity induced by different types of auditory stimuli. [Methods] We exposed 20 healthy you...

Immediate hypersensitivity to low molecular weight heparin (LMWH) is rare, and we present here a case with an anaphylaxis-like symptoms to enoxaparin. The diagnosis of hypersensitivity to enoxaparin was confirmed by the clinical picture and positive skin tests. In this case, palmo-plantal itching after application of heparin was an early sign of immediate type hypersensitivity. His skin and pro...