background : type 1 diabetes mellitus is the most common endocrine disease in pediatric. we aimed to determine the demographic characteristics at presentation of childhood type 1 diabetes mellitus in hamadan, west province of iran. methods : in this cross sectional descriptive study, demographic data of children with type 1 diabetes mellitus being followed up in pediatric endocrinology clinic o...

background and objective type 2 diabetes mellitus is a chronic, progressive illness that causes considerable morbidity and mortality. despite recent technical advances in therapy, more people are using alternative therapies. in this study evaluated the effect of sodium metavanadate on glucose levels and lipid profile in type 2 diabetes mellitus patients.   methods this is a randomized, controll...

background and objectives: studies have shown that many people with diabetes are fasting in the holy month of ramadan. ramadan fasting causes several changes in metabolism, habit and lifestyle that are associated with an increased risk of hypoglycemia and hyperglycemia in diabetic patients. an educational program based on behavioral science theory in the field of diet and medication changes, pr...

conclusions addition of fc decoction to oral hypoglycemic drugs might significantly decrease 2hpp in patients with dm type 2. it is a safe and inexpensive method. the mechanism for this decrease is something other than increased insulin secretion. results thirteen patients in each group completed the trial. fbs, fructosamine, hba1c, and c-peptide baseline and post-trial amounts in the case grou...

abstract objective: thyroid dysfunction complicates the metabolic derangement observed in diabetes mellitus (dm). it is necessary to recognize and treat it, when present, in order to achieve stability of metabolic control in these patients. the aim of this study was to investigate the effect of dm on thyroid hormone levels and other biochemical variables. materials and methods: to determine the...

OBJECTIVE To conduct a systematic review of cross-sectional and prospective human studies evaluating metabolite markers identified using high-throughput metabolomics techniques on prediabetes and type 2 diabetes. RESEARCH DESIGN AND METHODS We searched MEDLINE and EMBASE databases through August 2015. We conducted a qualitative review of cross-sectional and prospective studies. Additionally, ...

background osteoporosis and chronic kidney disease are common conditions in older adults, and often occur concurrently. bone disease is caused by increased bone turnover accompanying secondary hyperparathyroidism, and by factors such as bone metabolic disorder accompanying kidney disease and postmenopausal or age-related osteoporosis, even in hemodialysis patients. raloxifene is commonly used f...

t cells have been identified as key players in the pathogenesis of type 1 diabetes. however, the exact role of t-cell subpopulations in this pathway is presently unknown. the purpose of this study was to assess the expression pattern of two lineage-specifying transcription factors gata - 3 and t - bet , which are important in t helper type 1 (th1) and th2 cell development , respectively. gene e...

objective: the aim of the present study was to investigate the prevalence of hypertension and type ii diabetes in elderly iranianresidents of the kahrizak charity foundation(kcf). materials and methods: in this cross-sectional study, a total of two hundred sixty eight men and women ≥60 years were studied. the data were collected during annual health examination of the elderly residents in kcf. ...

background: diabetic nephropathy is considered to be the most common cause of end stage renal disease (esrd). proteinuria is declared as the most marked risk factor in progression towards esrd. the aim of this study was to evaluate the efficacy of pentoxifylline for reduction of proteinuria in type ii diabetic patients. methods: from may 2007 to june 2008, this randomized clinical trial study w...