OBJECTIVE To determine changes in chondrocyte transcription of a range of anabolic, catabolic and signaling genes following simultaneous treatment of cartilage with Insulin-like growth factor-1 (IGF-1) and ramp-and-hold mechanical compression, and compare with effects on biosynthesis. METHODS Explant disks of bovine calf cartilage were slowly compressed (unconfined) over 3-min to their 1mm cu...

A finite element model of wellbore stability was proposed for a horizontal well, and drill-string friction lateral collision in the process rotary motion were taken into account. An unconfined compression test used validation, normalized yielded zone area (NYZA) employed to analyze stability, influence on simulated. The results indicated that stress-strain curve numerical simulation consists wi...

The paper presents the test results from investigation of nature and mechanical behaviour mudbricks ancient mudbrick wall Eleusis in Attica, Greece. remains preserved to date site are some largest Small fragments were taken laboratory for experimental investigation. Testing included index tests toclassify soil material made of, mineralogical analyses their fines’ content, testing suitable mater...

Aeolian sand widely exists in the desert of western China. The reinforcement aeolian is considerable significance to construction transmission lines desert. In order study impact different cement contents and moisture content on performance cement-stabilized sand, 18 types samples with water were prepared. confined unconfined compression tests conducted TSZ series automatic triaxial instrument....

Flexible Polyurethane (PU) foam samples with different densities and chemical formulations were tested in quasi-static stress-strain compression tests. The compression tests were performed using the Lloyd LR5K Plus instrument at fixed compression strain rate of 0.033 s-1 and samples were compressed up to 70% compression strains. All foam samples were tested in the foam rise direction and their ...

Introduction Cartilage is a hydrated, load bearing and specialized tissue with unique biomechanical properties. Given its poor healing capacity, a number of tissue engineering and regenerative medicine strategies have emerged to address the repair of large cartilage defects. There has been significant Progress in this field, with various scaffolds, preconditioning bioreactors, and cell types ge...