نتایج جستجو برای: urotensin

تعداد نتایج: 551  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1995
T W Lovenberg C W Liaw D E Grigoriadis W Clevenger D T Chalmers E B De Souza T Oltersdorf

The present study reports the isolation of a cDNA clone that encodes a second member of the corticotropin-releasing factor (CRF) receptor family, designated as the CRF2 receptor. The cDNA was identified using oligonucleotides of degenerate sequence in a PCR paradigm. A PCR fragment obtained from rat brain was utilized to isolate a full-length cDNA from a rat hypothalamus cDNA library that encod...

Journal: :British journal of anaesthesia 2008
J P Williams J P Thompson S P Young S J Gold J McDonald D J Rowbotham D G Lambert

BACKGROUND The systemic inflammatory response to infection (sepsis) involves widespread organ dysfunction, including changes in immune modulation, cardiovascular derangements, and neural activation. Two neuropeptide/receptor systems, nociceptin/orphanin FQ (N/OFQ) which acts at the non-classical opioid receptor NOP and urotensin-II (U-II) which acts at the urotensin receptor (UT), have been imp...

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