Parkinson's disease is characterized by a progressive loss of dopaminergic neurons in the substantia nigra zona compacta, and in other sub-cortical nuclei associated with a widespread occurrence of Lewy bodies. The cause of cell death in Parkinson's disease is still poorly understood, but a defect in mitochondrial oxidative phosphorylation and enhanced oxidative and nitrative stresses have been...

G protein-gated, inwardly rectifying K+ channels (GIRK) are effectors of G protein-coupled receptors for neurotransmitters and hormones and may play an important role in the regulation of neuronal excitability. GIRK channels may be important in neurodevelopment, as suggested by the recent finding that a point mutation in the pore region of GIRK2 (G156S) is responsible for the weaver (wv) phenot...

Squash is associated with a high incidence of chronic injuries. Currently there is a trend in many sports for players to select minimalist footwear. The aim of the current investigation was to examine the effects of squashspecific, running shoes and minimalist footwear on the kinetics and 3-D kinematics of the lunge movement in squash players. Twelve male squash players performed lunge movement...

There is a scarcity of descriptive data on the physiological characteristics of elite Asian squash players. The purpose of this study was to evaluate the physiological profile and sports specific fitness of Hong Kong elite squash players. It was conducted before the selection of the Hong Kong national squash team for the 1992 Asian Squash Championship. Ten elite squash players were selected as ...

The new advances of having eight bands satellite mission similar to WorldView-2, WV-2, give the chance to address and solve some of the traditional problems related to the low spatial and/or spectral resolution; such as the lack of details for certain features or the inability of the conventional classifiers to detect some land-cover types because of missing efficient spectrum information and a...

The midbrain of the adult homozygous weaver (wv/wv) mouse is notable for a reduction in the numbers of dopamine-containing cells in the substantia nigra (A9) and the retrorubral nucleus (A8). We have determined that the reduction in tyrosine hydroxylase (TH)-positive neurons in the ventral midbrain of the weaver is attributable to the loss of neurons after postnatal day 7 (P7). Because the numb...

At the macrosopic level we study candidate 3D effective field theories associated to M theory in three dimensions. These represent analogs of 11D supergravity for eleven dimensional M-theory. At the microscopic level we study various world volume (WV) theories that can be used to relate world sheet (WS) theories of two dimensional strings. These are better defined for 3D targets than their 11D ...

Since 1988, cucurbit crops, particularly watermelon, cantaloupe, and squash, grown in Oklahoma and Texas have experienced devastating losses from cucurbit yellow vine disease (CYVD), caused by the phloem-limited bacterium Serratia marcescens Bizio. Squash bug, Anasa tristis (De Geer), is a putative vector of the pathogen. In 2000-2001, overwintering populations of squash bug collected from DeLe...