Uterine fatty tumours (UFT) are uncommon and have received little attention in the English literature. They have aroused interest as a consequence of occasional diagnostic confusion with sarcomas and the continuing unresolved dispute as to their histogenesis. Three cases of UFT are described and the pathological features of note discussed. The viewpoint that these tumours are hamartomas/chorist...

Uterine leiomyoma is the most common tumour in women with a reported incidence of 25-30%. The tumors are benign, composed of smooth muscle cells with variable amount of collagen - rich fibrous tissue. It is well established that accumulation of extracellular matrix in leiomyoma is key feature of tissue fibrosis. However, the pathogenesis of leiomyoma is still unclear. The aim of this study was ...

A case of xanthogranulomatous salpingitis (XGS) associated with a large uterine leiomyoma in a 50-year-old woman is presented. Xanthogranulomatous inflammation is an uncommon form of chronic inflammation that is destructive to affected organs. It is characterized by the presence of lipid-filled macrophages with admixed lymphocytes, plasma cells, and neutrophils. A review of the literature revea...

No doubt, uterine leiomyoma (UL) still the most common benign tumor of female reproductive system, affected about 80% of women during all reproductive age. The history of discovering referred to the times of Hippocrates, which firstly mentioned UL as “womb stones”. Later Galen depicted that condition as “scleromas”. The first “exhibition” of real samples with a high probability is situated in t...

Objective: To evaluate the efficacy of acrylamido polyvinyl alcohol hydrogel microspheres (A-PVAM) for uterine artery embolisation for leiomyoma in our centre in Hong Kong. Methods: This retrospective study reviewed cases that underwent uterine artery embolisation for symptomatic leiomyomas using A-PVAM from 2009 to 2012 in a single local institute. Preand post-embolisation magnetic resonance i...

Infertility can be influenced by several factors, including the presence of leiomyomas and tubal abnormalitieslike a abscess or tubo-ovarian which cause adhesions tubes surrounding tissuesor obstruction tubes. A 35-year-old woman is diagnosed with primary infertility 8 years withintramural uterine leiomyoma, right abscess, left obstruction.Laparotomy myomectomy salpingostomy surgery were carrie...

BACKGROUND Benign metastasizing leiomyoma (BML) occurs in a low proportion of uterine leiomyomas and treatment methods for BML are diverse and controversial. The study introduces preliminary experiences in the diagnosis and treatment of BML with the purpose of finding a suitable management strategy for these patients. METHODS Three patients with BML were treated in our department from April 2...

Endometrial stromal sarcoma (ESS) is very rare malignant tumor that constitutes approximately 10 % of all uterine sarcomas but only 0.2 % of all uterine malignancies [1]. ESS can be mistaken for leiomyoma because clinical presentation mimics each other and often needs HPE to establish correct diagnosis [2, 3]. In this article, we report a case of ESS in a young unmarried female of 23 years, whi...

We report two cases of uterine lipoleiomyoma in postmenopausal women of ages 52 and 55 years, who presented with complaints of leukorrhea and lower abdominal pain, respectively. Lipoleiomyoma is a rare benign variant of leiomyoma, having an incidence of 0.03%-0.2%. These are benign pelvic tumors which are usually asymptomatic and commonly occur in obese postmenopausal women. However, they can o...

OBJECTIVE Despite the high prevalence of uterine leiomyoma in women, little is known about the pathophysiology of this tumor. This study intends to define the epigenetic modulation of this tumor. METHODS Twenty-three pairs of leiomyomas and their adjacent myometria were collected. Status of DNA global methylation was determined by using DNA methyl acceptance assay and immunohistochemistry sta...