Primary intracranial germ cell tumors are rare, representing less than 5% of all central nervous system tumors. Overall, the majority of germ cell tumors are germinomas and approximately one-third are non-germinomatous germ cell tumors (NGGCT), which include teratoma, embryonal carcinoma, yolk sac tumor (endodermal sinus tumor), choriocarcinoma, or mixed malignant germ cell tumor. Germ cell tum...

Hydrometrocolpos Urogenital sinus Multiple malformations Abstract A case of hydrometrocolpos with vaginal opening to the bladder is presented. A newborn female presented abdominal distention and postaxial polydactyly at birth. Clinical investigation revealed hydrometrocolpos, precocious puberty, urogenital sinus and other multiple malformations. The vagina was open to the bladder with a small o...

hemangiomas of the sinonasal tract are rare, and because these lesions lack the typical signs or symptoms, they can be confused with other malignant conditions. we report a case of cavernous hemangioma of the maxillary sinus in a 68-year-old man that was completely resected by endoscopic sinus surgery. although computed tomography (ct) and magnetic resonance imaging (mri) showed several enhanci...

Pineoblastomas are rare, malignant pineal parenchymal tumors encountered predominantly in pediatric patients. They distinct from primitive neuroectodermal (PNET) at other sites that they exhibit photosensory differentiation including Flexner–Wintersteiner rosettes and fleu-rettes. Diagnosis can be challenging since share morphologic immunohistochemical fea-tures with embryonal the developing gl...

A growing body of evidence suggests that chronic low-grade inflammation and oxidative stress may lead to cancer development. These discoveries complement the usual focus prevention primarily concentrates on carcinomas, i.e., ectodermal or endodermal (embryonic) tissue-derived cancers, which are more exposed lifestyle/environment-related risk factors. Based these findings, preventive strategies ...

The patient is a seventheen years old girl, with severe pain and swelling in right maxillary sinus region and facial deformity from two weeks prior to referring. CT scan demonstrated a large tumoral mass in right maxillary sinus extended to petereigomaxillary fossa, orbital floor, lacrimal system and nasoethmoid region. Hard palate had been destroyed and bulged in to the oral cavity. Tumor was ...

OBJECTIVE To report a case of primary yolk sac (endodermal sinus) tumour (YST) of the vulva which is very rare and to highlight some unusual features of this tumour in the vulva. CLINICAL PRESENTATION AND INTERVENTION A 23-year-old woman presented with a 1-month swelling in the right labium majus that was non-tender and rapidly increasing in size. The mass was excised; it grossly measured 6 ×...

BACKGROUND Pineal tumors are very uncommon intracranial lesions, and endodermal cysts in this location are extremely rare. CASE DESCRIPTION A 49-year-old right-handed female presented with 3 weeks history of progressive dizziness and imbalance. Imaging studies showed 1.8 cm × 1.7 cm × 1.8 cm pineal lesion with small enhancing mural component displacing ventrally the quadrigeminal plate and na...

INTRODUCTION Low-grade endometrial stromal sarcoma (LG-ESS) is a malignant intrauterine tumor that rarely presents with distant metastasis. Simultaneous lung and cardiac metastases from LG-ESS is also an extremely rare event. CASE PRESENTATION A 42-year-old woman presented with dyspnea and exercise intolerance. She had a history of hysterectomy and left salpingoophorectomy. She underwent seco...

abstract we reported and analyzed an unusual case of npc (nasopharyngeal carcinoma) where the patient had initial clinical features of cavernous sinus involvement followed by trigeminal neuralgia and middle ear dysfunction. in the present case, the initial involvement of the cavernous sinus resulted in the left sided third nerve involvement. later on, the extension of the tumor in and around th...