Fibrous dysplasia (FD) is an osseous growth dis-order, producing immature bone and characte-rized by the replacement of normal bone with fibro-osseous connective tissue. It is a bone dys-plasia that has the potential to cause significant cosmetic and functional disturbances, particularly in the craniofacial skeleton. Cra-niofacial fibrous dysplasia is one of the three types of polyostotic fibro...

background & aim: regional odonto dysplasia (rod) is an unusual nonhereditary of teeth with significantly clinical and radiographic features. affected teeth usually remain unerupted or semi-erupted with a discolaration and irregular shape. radiographically these teeth have a large pulp chamber and thin layer of enamel and dentin with similar density. this article is introducing a female patient...

Development of the pulmonary circulation is a complex process with a spatial pattern that is tightly controlled. This process is vulnerable for disruption by various events in the prenatal and early postnatal periods. Disruption of normal pulmonary vascular development leads to abnormal structure and function of the lung vasculature, causing neonatal pulmonary vascular diseases. Premature babie...

colorectal cancer is the second leading cause of cancer death worldwide. through risk assessment of malignancy in polyps, screening programs can achieve the best results. this study aimed to determine the association between the grade of dysplasia and the location of colorectal polyps. 240 colorectal adenomatous polyps which were referred to department of pathology at rasoul-e-akram hospital be...

We studied the case records of all patients presenting with stage-I breast cancer (tumour < 2 cm, no axillary nodes or distant metastases). All clinical and pathological features were evaluated and findings were correlated with short term treatment failures (local and distant recurrences within 2 years). An early recurrence was seen in 28% patients. There was no significant differences in the m...

intracranial lipomas are congenital malformations. these uncommon lesions have an incidence of 0.1 to 1.7% of all intracranial tumors. most cases are located at midline and 5% are along the sylvian fissures. if symptomatic, seizures are the most common symptom. these tumors are slow growing and have favorable outcome. we report a case of a 25-year-old man whose ct and mri revealed a lesion in r...

dysplasia epiphysealis hemimelica is a rare nonhereditary epiphyseal disease that mimics synovial chondromatosis and osteochondroma of the joints. the disease mainly involves long bones of the lower extremities and tarsal bones. herein we report 21-year old woman who presented with pain and limited range of ankle motion, who underwent surgical excision of talus exostosis after preoperative imag...

BACKGROUND Distal alveolar morphogenesis is marked by differentiation of alveolar type (AT)-II to AT-I cells that give rise to the primary site of gas exchange, the alveolar/vascular interface. Endothelial-Monocyte Activating Polypeptide (EMAP) II, an endogenous protein with anti-angiogenic properties, profoundly disrupts distal lung neovascularization and alveolar formation during lung morphog...

Abstract Although coronavirus disease 2019 seems to be the leading topic in research number of outstanding studies have been published field aorta and peripheral vascular diseases likely affecting our clinical practice near future. This review article highlights key on 2020. Some shed light pathophysiology aortic aneurysm dissection suggesting a potential role for kinase inhibitors as new thera...