Vascular complications are extraintestinal manifestations of ulcerative colitis. Although there has been some controversy regarding the association between colitis and stroke, hypercoagulability systemic inflammation thought to be possible factors contributing stroke pathogenesis. Herein, we report a case recurrent ischemic with significant arterial stenosis. Cerebral vasculitis was suggested i...

background: anti-phospholipids syndrome (aps) is considered a non inflammatory auto-immune disease with a significant thrombophilic risk with varied clinical manifestations. the purpose of the current study was to investigate the frequency of thrombotic and non-thrombotic events in patients with aps. methods: in this retrospective study, 102 definite aps subjects were recruited (2007-2011) at a...

Background: The prevalence of anti-Neutrophil Cytoplasmic Antibodies (ANCAs) and anti-Cardiolipin Antibodies (anti-CL Ab) in Behcet’s Disease (BD) and also their roles in vascular involvement is controversial. Objective: To assess the prevalence of ANCAs and anti-CL Ab as well as their correlations with clinical manifestations in Iranian patients with BD. Methods: In this case/control study, th...

background: the aim of this study was to evaluate and compare the clinical and ‎electrocardiographic (ecg) manifestations of benzodiazepines (bzs).‎ methods: in this retrospective study, all bz-poisoned patients hospitalized at loghman ‎hakim hospital between september 2010 and march 2011 were evaluated. patients’ ‎information including age, sex, time elapsed between the ingestion and presentat...

background: oral lesions are among the earliest clinical manifestations of human immunodeficiency (hiv) infection and are important in early diagnosis and for monitoring the progression to acquired immunodeficiency syndrome (aids). the purpose of this study was to determine the prevalence of oral lesions and their relationship with a number of factors in hiv/aids patients attending an hiv cente...

OBJECTIVE to characterize the exocrine and non-exocrine clinical disease manifestations of 74 patients with primary Sjögren's Syndrome (pSS). METHODS retrospective study of pSS patients according to the new 2002 American-European criteria, followed in the Hospital Santa Maria, Rheumatology Outpatient Clinics, in the last 25 years (mean follow-up of 7.7 years). RESULTS all patients presented...

Chronic hepatitis C virus (HCV) infection is a growing global health problem. HCV is a leading cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC) and is associated with more than 30 extrahepatic manifestations (EHMs). Although cryoglobulinemia is the main pathological cause of neurologic EHMs, HCV viral replication in the brain itself must also be taken into consideration...

A 38-year-old woman was referred to our hospital for rheumatologic manifestations (migrant arthritis and tenosynovitis), without psoriasis or family history of psoriasis, gastroenteric manifestations, or recent genitourinary infections. The instrumental and laboratory tests have suggested a diagnosis of undifferentiated seronegative HLA-B27-positive spondyloarthritis with predominantly peripher...

The hyperdynamic syndrome is a late consequence of portal hypertension in cirrhosis. The principal hemodynamic manifestations of the hyperdynamic syndrome are high cardiac output, and increased heart rate and total blood volume, accompanied by reduced total systemic vascular resistance. Pathophysiology involves a complex of humoral and neural mechanisms that can determine hemodynamic changes, a...