background major vascular injury during a spinal surgery is a rare but most dreaded complication. case presentation a 39 years old female undergoing microscopic lumbar discectomy suddenly developed severe hypotension on table. the procedure was abandoned and the patient turned supine. it was diagnosed to be a major vessel tear and the patient was taken up for immediate successful vascular repai...

BACKGROUND AND OBJECTIVES Cognitive impairment is common among persons with chronic kidney disease, but the extent to which nontraditional vascular risk factors mediate this association is unclear. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS We conducted cross-sectional analyses of baseline data collected from adults with chronic kidney disease participating in the Chronic Renal Insufficien...

BACKGROUND Cardiovascular disease, which is due in part to progressive vascular calcification, is the leading cause of death among patients with end stage kidney disease (ESKD) on dialysis. A role for vitamin K in the prevention of vascular calcification is plausible based on the presence of vitamin K dependent proteins in vascular tissue, including matrix gla protein (MGP). Evidence from anima...

Diabetes mellitus (DM) per se confers a two-fold excess risk of vascular outcomes, but the is subject to wide variation depending on population and contemporary prophylactic medical therapy. Although patients with DM have high rate asymptomatic coronary heart disease (CHD), routine screening for CHD has not been shown improve clinical outcomes in being treated intensive therapy cardiovascular f...

The presence and pattern of iron accumulation in subcortical vascular mild cognitive impairment (svMCI) and their effects on cognition have rarely been investigated. We aimed to examine brain iron deposition in svMCI subjects using quantitative susceptibility mapping (QSM). Moreover, we aimed to investigate the correlation between brain iron deposition and the severity of cognitive impairment a...

BACKGROUND Contemporary war-related studies focus primarily on adults with few reporting the injuries sustained in local pediatric populations. The objective of this study is to characterize pediatric vascular trauma at US military hospitals in wartime Iraq and Afghanistan. METHODS Review of the Department of Defense Trauma Registry (DoDTR) (2002-2011) identified patients (1-17 years old) tre...

Vascular events are one of the major causes of death in case of Cushing's syndrome (CS). However, due to the relative low frequency of CS, it is hard to perform a risk assessment for these events. As represented congestive heart failure (C), hypertension (H), age (A), diabetes (D), and stroke (S), the CHADS2 score is now accepted to classify the risk of major adverse cardiovascular events (MACE...

BACKGROUND Patients who undergo vascular surgery are at increased risk of perioperative cardiovascular morbidity and mortality. The Revised Cardiac Risk Index (RCRI) is a validated and widely used bedside tool for estimating the risk of a perioperative major adverse myocardial event. We hypothesized that inclusion of the indication for surgery would add independent and prognostic information to...

AIMS To examine the effectiveness of the Montreal Cognitive Assessment (MoCA) to screen people with mild cognitive impairment (MCI), to associate the MoCA score with the presence of infarction, and to detect the characteristics of people with very mild subcortical vascular dementia (vmSVD). METHODS 392 out of 886 community dwellers aged 75 years and above living in Kurihara, Northern Japan, a...

BACKGROUND Atherothrombotic diseases including cerebrovascular disease (CVD), coronary artery disease (CAD), and peripheral arterial disease (PAD), contribute to the major causes of death in the world. Although several studies showed the association between polyvascular disease and poor cardiovascular (CV) outcomes in Asian population, there was no large-scale study to validate this relationshi...