BACKGROUND Livedoid vasculitis is a chronic dermatological problem with an unclear etiology. Clinical findings are petechiae with painful ulcers in both lower extremities, which heal to become hyperpigmented and porcelain-white satellite lesions. There are only a few reported cases of livedoid vasculitis presenting in combination with peripheral neuropathy. CASE REPORT We report the first cas...

Pathologic processes are underlying defining features of systemic vasculitis. When these pathologic processes can not be observed directly, surrogate signs and symptoms of disease must be used to conclude that vasculitis is present in a patient and, if so, to determine what specific type of vasculitis is present. This review briefly describes the most defining pathologic features of giant cell ...

Vasculitis is classified by the size of the blood vessels affected by inflammatory reactions. In vasculitis of skin, many patients show obvious purpura and ulceration. Because many vasculitides can be noticed by these skin manifestations, dermatologists should be well informed about vasculitis. It is difficult to manage vasculitis after the diagnosis has been performed, and it is particularly d...

The diagnosis of a primary vasculitic syndrome is dependent on documentation of vasculitis and the exclusion of diseases that can cause secondary vasculitis. The diagnosis of a specific primary vasculitic disorder depends on the pattern of organ involvement, the histopathology, and the size of affected blood vessels. The major determinants of prognosis and therapy include the type of vasculitis...

OBJECTIVE To report 3 patients with minocycline-induced autoimmunity resulting in peripheral nerve vasculitis. METHODS We report 3 patients who, during minocycline treatment for acne vulgaris, developed subacute onset of pain and weakness caused by vasculitis in single and multiple mononeuropathy patterns. RESULTS Each patient underwent either a nerve or muscle biopsy that confirmed vasculi...

Vasculitis is a rare disease in children, with IgA being its most common presentation. One condition that has been associated the development of vasculitis invasion vascular endothelium by Strongyloides stercoralis in cases hyperinfestation. Another not yet under-researched likely association vasculitis-like processes with SARS-CoV-2 and COVID-19 infection itself. ...

Systemic vasculitis is a heterogeneous group of disorders characterized by inflammation andnecrosis in the vessel wall. The diagnosis of a systemic vasculitis is challenging, because patients usually present a broad spectrum of manifestations that vary according to the predominant size of vessels affected, organs and systems involved, and the extent of the inflammatory process (1). In systemic ...

OBJECTIVE ANCA has come to play an important role in diagnosing vasculitis. In selected populations c-ANCA/PR3-ANCA has a high specificity and sensitivity for vasculitis. In clinical practice, how individuals with c-ANCA/PR3-ANCA but without sufficient evidence of systemic vasculitis should be managed is unclear. We therefore retrospectively assessed the disease panorama and outcome in a consec...

The term “vasculitis” includes a heterogeneous group of multisystemic disorders characterized pathologically by inflammation of blood vessels [1,2,3]. Inflammation can involve some, or all, of the thickness of the vessel wall. Immune complexes are a major component of vasculitis syndromes, and cellular mechanisms play a major pathogenic role in giant cell arteritis [4-12]. Arterial lesion can l...

Drug-induced vasculitis is a known side effect of prolonged treatment with several drugs. It is characterized by inflammation and cellular infiltration of small vessels and presence of anti-neutrophil cytoplasmic antibodies (ANCA). Propylthiouracil and hydralazine (anti-thyroid and antihypertensive drugs) are the drugs most commonly associated with drug-induced vasculitis. Small vessels of the ...