ACUTE venous thrombosis and its conmplilAw eations continue to be a challenging problem to the physician. Ineomplete understanding of the pathogenetic mechanisms, lack of objective measures for diagnosis, and differences of opinion coneerning therapy are parts of this problem. These difficulties, however, should not discourage the physician in his attempts to diagnose and treat venous thrombo-e...

BACKGROUND In about a third of patients with venous thromboembolism, the cause of the disorder is unexplained. In patients with atherosclerosis, activation of both platelets and blood coagulation and an increase in fibrin turnover are detectable, which may lead to thrombotic complications. Whether atherosclerosis is associated with an increased risk of venous thrombosis is unknown. METHODS We...

ACUTE venous thrombosis and its conmplilAw eations continue to be a challenging problem to the physician. Ineomplete understanding of the pathogenetic mechanisms, lack of objective measures for diagnosis, and differences of opinion coneerning therapy are parts of this problem. These difficulties, however, should not discourage the physician in his attempts to diagnose and treat venous thrombo-e...

BACKGROUND Increased homocysteine levels are related to the occurrence of venous thrombosis, but whether this relation is causal is unclear. The T-variant of the common methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism mildly increases homocysteine levels. Meta-analyses have demonstrated a weak effect of the MTHFR 677TT genotype on risk but are sensitive to selective publication...

Lupus anticoagulants (LA) can cause acquired activated protein C resistance (APC-R), but the clinical significance is unclear. To investigate thrombosis and acquired APC-R in patients with LA, we enrolled all 132 patients undergoing hypercoagulability testing with positive LA results and in whom APC-R (with factor V-deficient plasma) was performed during a 2.5-year period. Among 121 patients wi...

Introduction. Primary venous tumours are a rare cause of deep vein thrombosis. The authors present a case where the definitive diagnosis was delayed by inconclusive complementary imaging. Clinical Case. A thirty-seven-year-old female presented with an iliofemoral venous thrombosis of the right lower limb. The patient had presented with an episode of femoral-popliteal vein thrombosis five months...

OBJECTIVE To provide a comprehensive overview of the risk of venous thrombosis in women using different combined oral contraceptives. DESIGN Systematic review and network meta-analysis. DATA SOURCES PubMed, Embase, Web of Science, Cochrane, Cumulative Index to Nursing and Allied Health Literature, Academic Search Premier, and ScienceDirect up to 22 April 2013. REVIEW METHODS Observational...

Venous thrombosis is common in older age, with an incidence of 0·5-1% per year in those aged >70 years. Stasis of blood flow is an important contributor to the development of thrombosis and may be due to venous insufficiency in the legs. The risk of thrombosis associated with clinical features of venous insufficiency, i.e., varicose veins, leg ulcers and leg oedema, obtained with a standardized...

The incidence of clinically significant thrombosis in a cancer patient varies from 5 to 60%. Venous thrombosis remainsmore common than arterial thrombosis, and combined arterial and venous thrombosis in cancer patients is rare [1]. We report a rare case of combined pulmonary thromboembolism and complete thrombotic occlusion of the renal artery in a patient with non-small cell lung cancer (NSCLC...

BACKGROUND Cerebral venous sinus thrombosis is a common but highly under-recognised condition, which is missed not only by general practitioners but also by neurologists. Computerised tomography (CT) or magnetic resonance imaging (MRI) of brain alone is not sufficient to diagnose this condition. Objective of this study was to explore the pattern of magnetic resonance imaging (MRI) and magnetic ...