Several groups of drugs have been shown to possess antiarrhythmic activity. Some of them e.g. quinidine, procainamide, local anaesthetics, β-receptor blocking agents and diphenylhydantoin etc. have achieved a clinical status as antiarrhythmic drugs. Diphenyl hydantoin (dilantin) an anticonvulsant has been successfully employed for the supression of ventricular arrhythmias due to digitalis ...

The use of antiarrhythmic drugs to suppress ventricular arrhythmias in pediatric patients with a structurally or hemodynamically abnormal heart appears to improve long-term prognosis. The previously successful use of phenytoin to treat serious ventricular arrhythmias led to the investigation for an alternative antiarrhythmic agent, in the same antiarrhythmic drug class, for those patients who d...

Ventricular arrhythmias were recorded in 233 patients in a prospective study of patients with acute myocardial infarction. In over 95% of patients antiarrhythmic therapy was not given until the onset of ventricular tachycardia, ventricular fibrillation, or persistent idioventricular rhythm. There was a mortality of 18% during the patients' stay in hospital. The most important features of ventr...

The majority of left ventricular aneurysms occur as a consequence of ischaemic heart disease and healed myocardial infarction. Arrhythmias happen sometimes as complications of left ventricular aneurysm, and aneurysmectomy for the control of these arrhythmias was recently reported (Hunt, Sloman, and Westlake, I969). In contrast, aneurysm of the right ventricle is rare (Weglicki, Ruskin, and McIn...

Retrograde atrial preexcitation following premature ventricular beats during reciprocating tachycardia in the Wolff-Parkinson-White syndrome. Eur J Cardiol 3: 283, 1975 28. Rosen KM, Denes P, Wu D, Dhingra RC: Electrophysiological diagnosis and manifestation of dual A-V nodal pathways. In Conduction System of the Heart, edited by Wellens HJJ, Lie H, Janse MJ. The Netherlands, H.E. Stenfert Kroe...

Ventricular arrhythmia was once regarded uncommon in infants and children, since most cardiac arrests were thought to be hypoxia-induced bradycardia followed by asystole. Furthermore, ischemic heart disease, the basis for many of the ventricular arrhythmias in adults, is rare in pediatric patients. However, with the advent of pediatric critical care, improved techniques of extracorporeal life s...

BACKGROUND The risk factors for ventricular arrhythmias in patients with coronary vasospasm have not been identified. We evaluated QT dispersion in patients with vasospastic angina and its relation to susceptibility to ventricular arrhythmias during myocardial ischemia and reperfusion. METHODS AND RESULTS We assessed the corrected QT (QTc) dispersion before induction of coronary artery spasm ...

Endocardial and epicardial electroanatomical mapping and ablation is a safe and effective therapy in the treatment of right ventricle arrhythmias occurring in the setting of arrhythmogenic right ventricular cardiomyopathy (ARVD). Careful mapping and ablation plans must be tailored for each patient based on comorbidities and ventricular tachycardia morphologies. This review focuses on the cathet...

We report a 47 year-old male patient with coexistence of left ventricular noncompaction and Brugada syndrome. He presented malignant ventricular arrhythmias followed by cardioverter- -defibrillator implantation, atrial fibrillation and flutter and progressive heart failure. This case could be an example of the coexistence of two rare diseases of various genetic patterns that only partially show...