Present evidence suggests that in the small intestine, villus cells are primarily absorptive and crypt cells are primarily secretory. In order to further confirm that there are differences in transport properties between villus and crypt cells, we have separated villus from crypt cells, using calcium chelations techniques, and determined the distribution of Na:H and Cl:HCO3 exchange activity on...

The impact of a challenge with moderately pathogenic <em>Escherichia coli</em> O128:C6 on the digestive physiology and gut bacterial community growing rabbits under two feeding programmes was analysed. Upon weaning (28 d old), 180 were allocated to four groups (9 cages 5 per group) for weeks: group C100 non-inoculated fed <em>ad libitum</em>; C70 feed intake limited 70% ...

The present study investigated the growth performance, immune status, gut morphology, and microflora modulation in growing-to-finishing pigs (n = 72; 24 pigs/group) after dietary supplementation with Bacillus subtilis (B. subtilis; two groups (experiment 1 (E1) experiment 2 (E2): 63 98 days, respectively) control (Ct, basal diet). results revealed that both 1–98 d 1–63 significantly improved in...

The intestinal epithelium undergoes a marked adaptive response following loss of functional small bowel surface area characterized by increased crypt cell proliferation and increased enterocyte migration from crypt to villus tip, resulting in villus hyperplasia and enhanced nutrient absorption. Hedgehog (Hh) signaling plays a critical role in regulating epithelial-mesenchymal interactions durin...

Dietary fiber was used for reduce feed cost in local animal production. However, other advantages effects were interesting to study. Therefore, the objective of this research investigated effect source diet on performance, carcass quality, oxidative stress and intestinal morphology Thai native chicken. A total 300 one-day-old (mixed sex) crossbred chicks (Pradu Hang dum) randomly assigned 5 tre...

The effects of phytase and tannase enzyme treatment sorghum-based broiler diets on ileal villi characteristics were evaluated in Cobb 500 broilers. A total three sorghum levels, 0, 50, 100%, with 4 levels; 5% phytase, phytase+tannase combination used to develop 12 different dietary treatments. Three hundred sixty broilers randomly allocated the treatments a completely randomized design experime...

Aflatoxin B1 (AFB1) is a common contaminant of poultry feeds in tropical and subtropical climates. Early researches have well established the hepatotoxic, carcinogenic, and immunotoxic effects of AFB1 on humans and animals. Recently, it has been shown that AFB1 could cause the up- or down-alteration of mitochondrial pathway molecule expression. However, the information on the expression of deat...

Chlorogenic acid, a natural phenolic acid present in fruits and plants, provides beneficial effects for human health. The objectives of this study were to investigate whether chlorogenic acid (CHA) could improve the intestinal barrier integrity for weaned rats with lipopolysaccharide (LPS) challenge. Thirty-two weaned male Sprague Dawley rats (21 ± 1 d of age; 62.26 ± 2.73 g) were selected and ...

BACKGROUND & AIMS Celiac disease (CeD) provides an opportunity to study autoimmunity and the transition in immune cells as dietary gluten induces small intestinal lesions. METHODS Seventy-three celiac disease patients on a long-term, gluten-free diet ingested a known amount of gluten daily for 6 weeks. A peripheral blood sample and intestinal biopsy specimens were taken before and 6 weeks aft...

Purpose: To evaluate the effect of remote ischemic preconditioning (r-IPC) administered to pregnant rats, in the ileum of newborn rats subjected to hypoxia and reoxygenation. Methods: We used three pregnant rats and their newborn rats distributed in three groups: 1) Control (C) - Newborn rats born from a pregnant rat which did not undergo any intervention; 2) Hypoxia-Reoxygenation (H/R) - Ne...