Animal model : To study the possibility of a viral transmission through the use of the air pressure injector, we have chosen the mouse hepatitis viral infection as a mouse model since this virus is highly infectious and induces a fulminant hepatitis leading to a rapid death in selected mouse strains. The serotype 3 of MHV strain is the most virulent strain of this virus and induces hepatitis in...

Over the last four decades, the diagnosis and therapy of viral hepatitis has evolved substantially all over the world. Although Nepal is a developing nation, it has been keeping pace with these developments in terms of the implementation of diagnostic and therapeutic strategies. However, because of a lack of infrastructure and logistics, Nepal still depends on its neighboring countries for mole...

Chronic viral hepatitis is a public health issue both worldwide and in Romania, where the prevalence of the disease is still high. We present the available therapies used for chronic viral hepatitis B treatment in children, worldwide and in Romania, indications and contraindications of treatment, benefits and disadvantages for each class. The present paper reviews only the treatment options and...

The mechanisms that determine viral clearance or viral persistence in chronic viral hepatitis have yet to be identified. Recent advances in molecular genetics have permitted the detection of variations in immune response, often associated with polymorphism in the human genome. Differences in host susceptibility to infectious disease and disease severity cannot be attributed solely to the virule...

PURPOSE This study investigates whether patients with viral hepatitis and cirrhosis are at risk of uveitis in the years following hepatitis. METHODS We used data from Taiwan National Health Insurance system. The cases were patients newly diagnosed with viral hepatitis from 2000 to 2011. The end point of interest was a diagnosis of uveitis. A chi-square test was used for the difference of demo...

conclusions there is an as yet unexplained association between hcv and host parameters with unknown mechanisms in patients with chronic hcv infection. the assessments of core aa 70 substitution and polymorphisms near the ifnl3 gene could offer promising steps to improve the management of patients with hcv. background molecular studies have demonstrated that the hepatitis c virus (hcv) genotype ...

Hepatic injury is associated with distortion of the metabolic function. Hepatic disease can be evaluated by biochemical analysis of the serum tests, includes levels of serum Alanine and Aspartate aminotransferases, alkaline phosphatase, and others. The present study was conducted to assay Liver associated enzymes on patients with Viral Hepatitis, Alcoholic hepatitis and Chronic hepatitis and to...

Although false-positive antibodies (FPAs) have been well described in chronic hepatitis C virus (HCV), this has not been evaluated in acute viral hepatitis. Patients with acute viral hepatitis underwent antibody testing for other causes of liver disease and sexually transmitted diseases. Those with antibody positivity underwent confirmatory testing and monitoring. Patients with FPAs were compar...

Viral hepatitis, as an international public health concern, seriously affects communities and health system. In recent years, great strides have been taken for development of new potential tools against viral hepatitis. Among these efforts, a valuable strategy introduced new molecules called "aptamers". Aptamers as potential alternatives for antibodies could be directed against any protein in i...

transfusion-transmissible infections such as hepatitis b and hepatitis c are among the greatest threats to blood safety for transfusion recipients and pose a serious public health problem. the aim of this study was to assess the epidemiological aspects of hepatitis b and c in kazakhstani donor's blood over the period 2000-2011.the data were obtained from the annual reports of the republican blo...