Introduction: Multiple sclerosis is a chronic inflammatory disease of central nervous system. The etiology of MS is slightly known, but genetic and environmental factors are reported. Vitamin D regulates gene expression and affects target cell functions. The aim of this study was to investigate the expression variation of IL-2 and IL-4 genes under vitamin D supplementation in patients with mult...

OBJECTIVE The purpose of our study was to compare vacuum-assisted suction drainage (VASD) to conventional wound management, in the treatment of poststernotomy osteomyelitis (SOM). METHODS We included a total of 42 patients that developed poststernotomy osteomyelitis and required open wound management, between 1998 and 2000, in this study. Twenty of these patients were treated by VASD and the ...

BACKGROUND Mortality due to severe pneumonia during childhood in resource-constrained settings is high, but data to provide basis for interventions to improve survival are limited. The objective of this study was to determine the risk factors for severe pneumonia in children aged under five years old in Mwanza, Tanzania. METHODS We conducted a case-control study of children aged 2 to 59 month...

vitamin e (alpha-tocopherol) is a potent and natural antioxidant. vitamin e is concentrated from soybean oil. the committee on fetus and newborn of the academy of the american of pediatrics endorsed 1 to 2 mg/dl as the normal range of serum tocopherol level. human infants are born with low stores of vitamin e, thus they require an adequate intake of vitamin e soon after birth. the optimum intra...

Objective: Diabetes mellitus is a metabolic disorder associated with impaired serum skeletal muscle pain enzymes levels. The purpose of this study was to investigate the effect of 8 weeks aerobic training with and without vitamin C consumption on serum levels of Creatine Kinase (CK) in type 2 diabetic patients (T2DM). Materials and Methods: In this clinical trial 45 women (30-45 years) with T2...

Obesity is often associated with vitamin D deficiency and secondary hyperparathyroidism. Vitamin D supplementation typically leads to the reductions in serum parathyroid hormone (PTH) levels, as shown in normal weight individuals. Meanwhile, the dose of vitamin D supplementation for the suppression of PTH may differ in overweight and obese adults. We conducted a systematic review and meta-analy...

INTRODUCTION Vitamin A is important for the integrity and regeneration of respiratory and gastrointestinal epithelia and is involved in regulating human immune function. It has been shown previously that vitamin A has a preventive effect on all-cause and disease specific mortality in children under five. The purpose of this paper was to get a point estimate of efficacy of vitamin A supplementat...