BACKGROUND Vitamin D deficiency is a re-emerging epidemic, especially in minority populations. Vitamin D is crucial not only for bone health but for proper brain development and functioning. Low levels of vitamin D are associated with depression, seasonal affective disorder, and schizophrenia in adults, but little is known about vitamin D and mental health in the pediatric population. METHODS...

Background: Vitamin B-12 deficiency is usually accompanied by elevated concentrations of serum total homocysteine (tHcy) and methylmalonic acid (MMA). Folate deficiency also results in elevated tHcy. Measurement of these metabolites can be used to screen for functional vitamin B-12 or folate deficiency. Objective: We assessed the prevalence of vitamin B-12 and folate deficiency in a population-...

Migraine is a disabling headache disorder. That is characterized by recurrent unilateral pulsatile headaches. It is one of the most common neurological disorder in the world that nearly one billion of people are affected by migraines. The main Migraine’s features are headaches. Accompanying symptoms are nausea, sometimes vomiting, photophobia, neck pain and muscle tension. Its attacks las...

background: vitamin b12 (cobalamin) deficiency can result in some clinical and paraclinical characteristics similar to what is seen in multiple sclerosis (ms) patients. this study aimed to evaluate the controversial association between vitamin b12 deficiency and ms. methods: we measured serum vitamin b12 in 60 patients with ms and 38 healthy controls. clinical disability was evaluated according...

introduction: elevated plasma total homocysteine is an independent risk factor for cardiovascular disease and a sensitive marker of vitamin b12 and folate insufficiency. folate and vitamin b12 have a protective effect on cardiovascular disease. this effect may be partly explained by mechanisms independent of homocysteine. this survey is the first population based study to evaluate the plasma to...

background: metabolic syndrome (ms) is an important risk factor that is associated with vitamin d deficiency, according to recent studies. this study aimed to evaluate the relationship between serum 25-hydroxyvitamin d level and risk of metabolic syndrome in children in birjand. materials and methods: a case-control study on 6 to 18 years old metabolic syndrome patients, this investigation was ...

Although vitamin K deficiency has been implicated in adult inflammatory bowel disease (IBD), its prevalence in pediatric IBD remains unknown. We carried out a cross-sectional study in 63 children with Crohn's disease (CD) and 48 with ulcerative colitis (UC) to assess the prevalence of vitamin K deficiency and to search for potential correlation between vitamin K status and pediatric IBD activit...

Vitamin D is a vitamin not only associated with calcium-phosphorus metabolism but also affects many organ systems. Because of its effect on the immune system in recent years, it has attracted much attention. Vitamin D deficiency is a clinical condition that can be widely observed in the society. Thus, patients with vitamin D deficiency are often seen in anaesthesia practice. In the absence of v...

Vitamin A deficiency produces anemia and altered iron status. In this study with rats we tested two hypotheses regarding vitamin A deficiency: (1) that it impairs erythropoiesis, leading to an increased red cell turnover, and (2) that it inhibits the glycosylation of transferrin. Erythropoietic activity was assessed indirectly by determining the myeloid:erythroid ratio in bone marrow smears, th...

Low plasma level of vitamin D is linked to the increased risk of cardiovascular diseases such as hypertension, diabetes, dyslipidemia and peripheral vascular diseases. Vitamin D deficiency is a worldwide problem that involves Iranian population. To the best of our knowledge, this was the first investigation on venous thromboembolism (VTE) subjects that assessed the correlation of vitamin D leve...