We present similarity solutions for adiabatic bubbles that are blown by winds having time dependent mechanical luminosities and that are each mass-loaded at a rate per unit volume proportional to T r, where T is the temperature, r is the distance from the bubble center, and λ is a constant. In the limit of little mass loading a similarity solution found by Dyson (1973) for expansion into a smoo...

In tree-length harvesting operations, the trees are usually delimbed and topped in the woods. Sawlogs are bucked, and pulpwood is loaded tree-length. The use of in-woods chipping has been limited to energywood production because high bark content limits the use of whole-tree chips as pulp furnish. Flail delimbing and debarking allows economical processing and chipping of whole trees in the wood...

Peak stresses acting in limb bones should increase with increasing size if the forces acting on the bones increase in direct proportion to the animal's body weight. This is a direct consequence of the scaling of limb bone geometry over a wide range in size in mammals. In addition, recent work has shown that the material strength of bone is similar in large and small animals. If the assumptions ...

The glutamine analogue, 6-diazo-5-oxo-L-norleucine (DON), has been shown to inhibit biosynthesis of purines and glycosaminoglycans, presumably by blocking the glutamine-dependent steps in the biosynthetic pathways. The teratogenic potential of DON on the developing mouse limb-bud in vivo and in vitro was studies in an attempt to discriminate whether DON is exerting its teratogenic effect by int...

Our aim was to test cell and trabecular responses to mechanical loading in vitro in a tissue bone explant culture model. We used a new three-dimensional culture model, the ZetOS system, which provides the ability to exert cyclic compression on cancellous bone cylinders (bovine sternum) cultured in forced flow circumfusion chambers, and allows to assess mechanical parameters of the cultivated sa...

abstractthe aim of the present study was to formulate poly (lactide-co-glycolide) (plga) nanoparticles loaded with 18-β-glycyrrhetinic acid (gla) with appropriate physicochemical properties and antimicrobial activity. gla loaded plga nanoparticles were prepared with different drug to polymer ratios, acetone contents and sonication times and the antibacterial activity of the developed nanopartic...

BACKGROUND Three-dimensional (3-D) type I collagen gel culture systems allow long-term growth of osteoblast-like cells, in vitro. Whether the implantation of 3-D collagen systems can stimulate new bone formation was assessed in male rabbits. MATERIALS AND METHODS A 10-mm segmental diaphyseal defect was surgically produced at the left and right limbs of 50 adult male rabbits. The 3-D systems c...

The world's population is aging rapidly, particularly in developed countries. The trend toward prolonged life expectancy will increase the elderly population and thereby lead to an increase in occurrences of age-related health problems such as chronic disease. Healthcare services and home-based rehabilitation are in high demand, and the demand for professional physical therapy is imposing an in...