OBJECTIVES It is largely unknown why extravascular lung water may increase during fluid loading in the critically ill with presumed hypovolemia. In this study we evaluated the hemodynamic predictors of such an increase. DESIGN A prospective observational study. PATIENTS Sixty-three presumed hypovolemic mechanically ventilated patients (22 septic and 41 nonseptic patients). INTERVENTION Fl...

In order to measure cerebral atrophy due to neurodegenerative diseases, the major confounding factor of normal age-related atrophy must be taken into account. Furthermore, in order to compare cerebral volume measurements across multiple subjects, normalisation for differences in head size is also required. We describe an investigation of these normalisations based on measurements of cerebro-spi...

Volume change and pressure development in muscle during contraction. 1967.-Volume changes recorded in isometric and isotonic twitches of gastrocnemius muscle are similar to those recorded in sartorius muscle. The major differences are the greater difficulty in approaching isometric recording conditions in the gastrocnemius muscle and the possibility that a portion of the volume change could be ...