Introduction Functional connectivity mapping using fMRI, first described over 10 years ago by Biswal, has recently gained in popularity. This approach utilizes BOLD fMRI signals obtained with subjects in the resting-state. Brain regions with high resting state connectivity are thought to be involved in the same network and the more well-formed the network, the stronger the connectivity. All of ...

The effect of T1 signal on FSL voxel-based morphometry modulated GM density and FreeSurfer cortical thickness is explored. The techniques rely on different analyses, but both are commonly used to detect spatial changes in GM. Standard pipelines show FSL voxel-based morphometry is sensitive to T1 signal alterations within a physiologic range, and results can appear discordant between FSL voxel-b...

We developed a method that transforms a polygonal representation of an object into a voxel representation on a 3D regular grid. By applying scale-space theory we derived expressions for an anti-aliased voxel representation of points, lines, and triangles. The algorithm ‘paints’ the triangles on the voxel grid and ‘fills’ the resulting surface. The method can be applied in 3D (medical) imaging a...

Abstract Deformable image registration (DIR) is an important component for dose accumulation and associated clinical outcome evaluation in radiotherapy. However, the resulting deformation vector field (DVF) subject to unavoidable discrepancies when different algorithms are applied, leading dosimetric uncertainties of accumulated dose. We propose here approach proton therapy estimate as a conseq...

Introduction: This study aimed to assess the effect of controlled mouth breathing during the resting state using functional magnetic resonance imaging (fMRI). Methods: Eleven subjects participated in this experiment in which the controlled “Nose” and “Mouth” breathings of 6 s respiratory cycle were performed with a visual cue at 3T MRI. Voxel-wise seed-to-voxel maps and whole-brain region of i...

Annually, many people are irradiated for diagnostic and therapeutic purposes. Assessment of radiation dose and its related risks to patients are important issues in radiation protection dosimetry. The complex mathematical calculations of the absorbed and effective doses are now done with computers. The calculations are performed with the help of anthropomorphic computational models of human bod...

BACKGROUND 3D ultrasound volume reconstruction from B-model ultrasound slices can provide more clearly and intuitive structure of tissue and lesion for the clinician. METHODS This paper proposes a novel Global Path Matching method for the 3D reconstruction of freehand ultrasound images. The proposed method composes of two main steps: bin-filling scheme and hole-filling strategy. For the bin-f...

Voxel models are of increasing interest in 3D computer games, as they give rise to many efficient operations that can not be performed easily on adaptive surface models like triangle meshes. Examples include the efficient generation of level of detail hierarchies and model modifications like carving and extruding. However, to faithfully represent the surface and, thus, to render it in a similar...

Internal dosimetry on non-human biota is getting more important from the viewpoint of radiation protection of the environment. The International Commission on Radiological Protection (ICRP) proposed the Reference Animals and Plants using simplified phantoms, such as ellipsoids and spheres, and assessed absorbed fractions (AFs) for the whole bodies. In this study, photon and electron AFs in whol...

This study investigated how sample size affects the reproducibility of findings from univariate voxel-based lesion-deficit analyses (e.g., voxel-based lesion-symptom mapping and voxel-based morphometry). Our effect of interest was the strength of the mapping between brain damage and speech articulation difficulties, as measured in terms of the proportion of variance explained. First, we identif...