نتایج جستجو برای: weinberg equilibrium the allelic
تعداد نتایج: 16068730 فیلتر نتایج به سال:
BACKGROUND/AIMS Preeclampsia (PE) is a systemic inflammatory response syndrome involving varieties of cytokines, and previous studies have shown that IL-33 and its receptor IL-1RL1 play pivotal roles in the development of it. As a polygenetic hereditary disease, it is necessary to study the gene analysis for PE. Therefore, the present study was to determine whether IL-33 rs3939286 and IL-1RL1 r...
The beta-casein locus with different allelic forms of A1 and A2 has been reported among many breeds of dairy cattle. These allelic forms produce beta-casein variants of A1 and A2. The bioactive peptide of beta-casomorphin-7 is produced from proteolysis of beta-casein A1 variant. Beta-casomorphin-7 has morphine like activity and results in some diseases including type 1 diabetes mellitus, cardio...
Allozyme genetic variability in five natural populations of Cyclobalanopsis championii (Fagaceae) in Taiwan was investigated using 12 loci from 9 enzyme systems. The average values of parameters describing within-population variation, expected heterozygosity (He = 0.151), the percentage of polymorphic loci per individual (P = 50%), the average number of alleles per locus (A = 1.7), effective nu...
Allele and genotype frequencies for 15 short tandem repeat (STR) polymorphisms--D3S1358, TH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta D, vWA, D8S1179, TPOX and FGA--in a Japanese population were estimated. No deviations of the observed allele frequency from Hardy-Weinberg equilibrium expectations were found for any of the systems studied. Between 2 new pentanuc...
INTRODUCTION Accumulating evidences show that shared autoimmunity is critical for the pathogenesis of many inflammatory rheumatic conditions. Specific phenotype could arise from specific genes, and/or combination of genetic factors and environment. Systemic sclerosis (SSc) belongs to connective tissue disorders and recent data have highlighted strong associations with some autoimmunity genes sh...
The use of translocations to establish new or ‘refuge’ populations for species with high conservation value is controversial but widely used in management. One the risks this approach that an establishing population does not adequately capture genetic diversity donor gene pool. This effect, rarely examined, tested here. In study consequences two after five generations (16 years) European whitef...
Microsatellite genotyping from samples with varying quality can result in an uneven distribution of errors. Previous studies reporting error rates have focused on estimating the effects of both randomly distributed and locus-specific errors. Sample-specific errors, however, can also significantly affect results in population studies despite a large sample size. From two studies including six mi...
We characterized 24 polymorphic tetranucleotide microsatellite loci for delta smelt (Hypomesus transpacificus) endemic to the San Francisco Bay Estuary, CA, USA. Screening of samples (n = 30) yielded two to 26 alleles per locus with observed levels of heterozygosity ranging from 0.17 to 1.0. Only one locus deviated from Hardy-Weinberg equilibrium, suggesting these individuals originate from a s...
The pituitary-specific transcription factor (PIT-1) gene is a candidate gene for growth, carcass and also for milk yield traits. In dairy farm animals, the main goal of the selection is the improvement of milk yield and composition. The genes of milk proteins and hormones are excellent candidate genes for linkage analysis with quantitative trait loci (QTL) because of their biological significan...
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