Sry is the only gene on the Y chromosome that is required for testis formation in mammals. One of the earliest morphological changes that occurs as a result of Sry expression is a size increase of the rudimentary XY gonad relative to the XX gonad. Using 5'-bromo-2'-deoxyuridine (BrdU) incorporation to label dividing cells, we found that the size increase corresponds with a dramatic increase in ...

The papaya plant Carica papaya (family: Caricaceae), locally known as Papita, is cultivated commonly in different parts of Sindh-Pakistan specially in Karachi. It was reported hermaphrodite. Recently it has been reported to be an important plant, due to having X and Y chromosomes. As it has been already reported that the papaya sex chromosomes have virtually all of the features that the human s...

A key decision in the life of an organism is whether to be male or female. In Drosophila, each cell makes this choice independently of its neighbors such that diploid cells with one X chromosome (XY) are male and those with two chromosomes (XX) are female. In classic experiments carried out more than 80 years ago, Calvin Bridges made two important conclusions about how sex is determined in flie...

BACKGROUND The aim of this study is to review and present the clinical features and process of evaluation and treatment for OT-DSD in a single center in recent years in China. METHODS Sixteen patients with OT-DSD during the past 4 years underwent the evaluation and treatment in a single center. The clinical characteristics and outcomes of surgery were analyzed. RESULTS The surgical age rang...

Pf62-Y and Pf62-X is a pair of allelic Y chromosome-linked and X chromosome-linked markers, and have been used to identify YY super-males, XY males and XX females for commercial production of all-male populations in yellow catfish (Pelteobagrus fulvidraco). However, the SCAR primers used previously have only two nucleotide difference, which restricts the wide utility because of nucleotide polym...

Dosage compensation is a fundamental mechanism in many species that corrects for the inherent imbalance in X-chromosome copy number between XY males and XX females. In Drosophila melanogaster, transcriptional output from the single male X-chromosome is equalized to that of XX females by recruitment of the Male Specific Lethal (MSL) complex to specific sequences along the length of the X-chromos...

Within the nematode genus Caenorhabditis, Caenorhabditis briggsae and C. nigoni are among the most closely related species known. They differ in sexual mode, with C. nigoni retaining the ancestral XO male-XX female outcrossing system, while C. briggsae recently evolved self-fertility and an XX-biased sex ratio. Wild-type C. briggsae and C. nigoni can produce fertile hybrid XX female progeny, bu...

      Background and aims: <span style="color: #221e1f; font...

  Background and aims: <span style="color: #221e1f; font-family: Optima LT St...

In the mouse, germ cells can undergo differentiation to become either oocytes or spermatozoa in response to sex of their gonadal environment. The nature of the germ cell-intrinsic aspects of this signaling have not been well studied. The earliest known sex-specific difference in germ cells is the initiation of meiosis in female, but not male, embryonic germ cells. Experiments were performed sho...