The pharmacokinetics of total and free prednisolone (PSL) in six healthy men, with or without pretreatment with oral glycyrrhizin (GL), was investigated to confirm whether oral administration of GL influences the metabolism of PSL in man. Each subject received an intravenous administration of 0.096 mg/kg of prednisolone hemisuccinate (PSL-HS) with or without pretreatment with 50 mg of oral GL f...

The present study was aimed to use spent wash as a substitute for expensive commercial media for Rhizobial cultures. Growth of Rhizobium strains at different concentrations of spent wash was observed and found maximum at 50% spent wash. Bacteria were grown on 50% spent wash which produced remarkable results and competed with standard media like tryptone yeast extract, Rhizobium minimal and yeas...

The anticandidal activity of the methanolic extract of Wedelia chinensis leave was studied and tested against four pathogenic Candida albicans strains of clinical isolates. The extract exhibited favorable anticandidal activity with the zones of inhibition between 18.00 ± 0.10 to 20.00 ± 0.17 mm and minimum inhibition concentration (MIC) values between 3.13 and 6.25 mg/mL. The time-kill studied ...

INTRODUCTION The livertaxis of glycyrrhizic acid-conjugated bovine serum albumin (GL-BSA) has been reported in the literature. Now, in this paper, we describe a novel type of drug-targeted delivery system containing 10-hydroxycamptothecin (HCPT) with liver tumor targeting. METHODS First, GL was coupled to BSA then HCPT was encapsulated in GL-BSA by high-pressure homogenization emulsification....

The composition factors of Kac-modules for the general linear Lie superalgebra gl m|n is explicitly determined. In particular, a conjecture of Hughes, King and van der Jeugt in [J. Math. Phys., 41 (2000), 5064-5087] is proved.

Background and Objectives: Preparation and evaluation of nanocomposite films have become prevalent in recent years. Depending on the purpose of using the film, and considering the effects and interaction effects of nanomaterial and other modifiers on the film properties, the amounts of nanomaterials and modifiers should be optimized. The effects of montmorillonite (MMT), glycerol (GL), and thei...

To study the import of proteins into mitochondria we developed a homologous in vitro system in which mitochondria and cell-free translation extract are both derived from the yeast Saccharomyces cerevisiae. This system allows the synthesis of precursor proteins in the presence of isolated mitochondria and offers a means of analyzing yeast mutants defective in mitochondrial protein import. The in...

Purpose: Aloe buettneri A. Berger is commonly used in Togolese folk medicine to treat inflammation and gastric ulcer. In this study we investigated the anti-oedema, analgesic, antipyretic and ulcer healing properties of the hydro-alcohol extract of their leaves. Methods: Rat oedema paw were induced by the injection of 0.1 ml of formaldehyde 1%, tail flick method is used to study analgesic prope...