an outbreak of zoonotic cutaneous leishmaniasis caused by leishmania major was identified in ghanavat rural district, qom province, central iran, during 1999-2001. among 1069 inhabitants examined in dec. 1999, 5.14% showed evidence of active lesions and 12.44% had scar indicative of past infection. the most highly infected age group was 5-9 years old for ulcers with a rate of 6.56%. the inciden...

Leishmaniases are parasitic diseases occurring in endemic tropical and subtropical areas and caused by protozoa of the genus leishmania, transmitted by a diptera (sand fly). We here report a case of topical cutaneous leishmaniasis discovered in a 15-year old boy with painless ulcer on his left leg, who had been staying in South Africa. Clinical examination showed painless non-itchy ulcer, occur...

Cutaneous leishmaniasis caused by various species of Leishmania is a significant zoonotic disease in many parts of the world. We describe the first cases of Australian cutaneous leishmaniasis in eight northern wallaroos, one black wallaroo and two agile wallabies from the Northern Territory of Australia. Diagnosis was made through a combination of gross appearance of lesions, cytology, histolog...

Cutaneous leishmaniasis is a very complex disease involving multiple factors that limit its emergence and spatial distribution. Prediction of cutaneous leishmaniasis epidemics in Tunisia remains difficult because most of the epidemiological tools used so far are descriptive in nature and mainly focus on a time dimension. The purpose of this work is to predict the potential geographic distributi...

Background: Cutaneous Leishmaniasis, is endemically observed in different parts of Iran in two forms of anthroponotic and zoonotic. The identification of both species and the type of disease are beneficial for treatment and prevention. Microscopic identification of Leishmania species has not provided promising efficacy. The aim of this study was to determine the Le...

background: characterization of leishmania parasites is necessary for epidemiological objectives such as documenting the distri­bution of predominant species and designing appropriate control measures. in this study, we aimed to identify leishma­nia species isolated from cutaneous leishmaniasis (cl) patients, using rapd-pcr method. methods: this descriptive, cross-sectional study was designed a...

Different molecular-genetic methods were used to identify a cohort of Leishmania strains from natural foci of zoonotic cutaneous leishmaniasis located in Central Asia, on the former USSR territory. The results obtained using isoenzymes, PCR, restriction fragment length polymorphisms of kDNA and molecular hybridization techniques are discussed in terms of their applicability, discrimination powe...

BACKGROUND Sand fly saliva compounds are able to elicit specific immune responses that have a significant role in Leishmania parasite establishment and disease outcome. Characterizing anti-saliva immune responses in individuals living in well defined leishmaniasis endemic areas would provide valuable insights regarding their effect on parasite transmission and establishment in humans. METHODO...

Canine leishmaniasis is a chronic parasitic disease transmitted by small bloodsucking insects. Clinically, affected patients present with progressive wasting, slight or marked reduction in appetite, lymphadenomegaly, splenomegaly, and cutaneous lesions (e.g., dry desquamation [dry seborrhea], ulcers, nodules). A correct diagnosis is based on specific serologic and molecular tests and nonspecifi...