DNA damage in HeLa nuclei and isolated nucleosome core particles has been examined for several members of the enediyne family of antitumor antibiotics: calicheamicin gamma 1I (CAL), esperamicin A1 (ESP A1), esperamicin C (ESP C), and neocarzinostatin (NCS). In nuclei, both NCS and ESP A1 produced DNA damage limited to the linker region of the nucleosome, while CAL and ESP C, an analog of ESP A1...

OBJECTIVES The enterococcal surface protein gene, esp, is a major putative pathogenicity marker in clinical isolates of Enterococcus faecium and Enterococcus faecalis. This study demonstrates in vitro conjugative transfer of the esp gene among E. faecium and E. faecalis. MATERIALS AND METHODS Enterococcal isolates from clinical samples, positive for esp, were mated on filters with enterococca...

Advanced ESP consists of an HCU with built-in wheel pressure sensors. By using pressure feedback control, Advanced ESP reduces noise and improves pressure control performance. The system can be used for various value-added functions such as Stop & Go and regenerative braking. These additional functions require normal operation at all times. However, if Advanced ESP operates without detecting HC...

The ESP Game tends to generate “low effort” or “surface semantics” tags. This paper presents two variations of the ESP Games called “squaring” and “scripting” that trim the ESP Game to collect “deep semantics” tags. The approaches do not require players to get used to, and for the GWAP operators to deploy, new games. First experiments point to the efficiency of squaring and scripting the ESP Ga...

BACKGROUND AND STUDY AIMS Esophageal squamous papilloma (ESP) is a rare lesion. The aims of this study were to assess the prevalence of ESP in northeastern France and the risk of associated squamous cell carcinoma (SCC). PATIENTS AND METHODS The charts of 78 patients who were diagnosed with ESP between January 2005 and February 2013 at three hospitals in northeastern France were reviewed. R...

The locus of enterocyte effacement (LEE), which includes five major operons (LEE1 through LEE4 and tir), enables enterohemorrhagic Escherichia coli (EHEC) O157:H7 to produce attaching and effacing lesions on host cells. Expression of LEE2, LEE3, and tir is positively regulated by ler, a gene located in LEE1. Transcriptional regulation of the esp operon (LEE4), however, is not well defined. Tran...

ESP can help the road vehicle to improve driving dynamics and prevent accidents which result from loss of control. Based on the theory and account method of Multi-body System Dynamics, the Multi-body System Dynamics model of an A-class car is built by the ADAMS/Car software, which includes steering system, front and rear suspension, braking system, body, and so on. In order to study the handlin...

Chicken eggshell powder (ESP) might be an attractive source of Ca for human nutrition. To study its nutritional value, we analyzed minerals, amino acids, and hormones in commercially available Slovakian ESP. The mineral composition was compared with three Dutch ESP samples that differed in feed and housing, a Japanese ESP, refined CaCO3, and an oyster shell supplement. Chicken eggshell powder c...

هدف: سکوت سازمانی پدیده‌­ای رایج و متداول در سازمان­‌ها واقعیتی موجود ملموس برای مدیران کارکنان است. یکی از موانع مهم موفقیت برنامه‌­ها اهداف سازمان، فقدان اطلاعات، اعتماد آن چیزی است که پژوهشگران را نام نهاده‌­اند عبارت خودداری بیان ایده‌­ها، نظرات اطلاعات راجع به مشکلات سازمانی. سویی دیگر قصد ترور روحی با ایجاد فشار روانی روی شخص مورد هدف، دورکردن هویت استفاده فشارهای منظم مستمراست. توجه اینک...