We investigated if the refractoriness to the tocolytic effects of atrial natriuretic factor (ANF) during rat pregnancy is due to a downregulation of one or both guanylyl cyclase (GC)-coupled GC-A and GC-B ANF receptors; lungs were used as controls. Uteri and lungs of virgin, pregnant ( days 7, 16, and 21), and day 2postpartum rats expressed mRNAs for GC-A and GC-B as well as GC-uncoupled ANF-C ...

We introduce Free Hash, a new approach to generating Garbled Circuit (GC) hash at no extra cost during GC generation. This is in contrast with state-of-the-art approaches, which hash GCs at computational cost of up to 6× of GC generation. GC hashing is at the core of the cut-and-choose technique of GC-based secure function evaluation (SFE). Our main idea is to intertwine hash generation/verific...

The nucleotide composition of genomes undergoes dramatic variations among all three kingdoms of life. GC content, an important characteristic for a genome, is related to many important functions, and therefore GC content and its distribution are routinely reported for sequenced genomes. Traditionally, GC content distribution is assessed by computing GC contents in windows that slide along the g...

Microsatellite instable gastric cancer (MSI-GC) is a specific molecular subtype of GC. We studied the phenotypes, genotypes, and clinicopathologic characteristics of MSI-GC in a white GC cohort and compared our findings with an extended literature review. The study cohort consisted of 482 patients. Specimens were available from 452 cases and were used for immunostaining (MLH1, PMS2, MSH2, MSH6)...

Garbage collection (GC) normally causes pause of execution. Parallel GC has a great potential for real time (non-disruptive) processing. A traditional parallel mark and sweep GC algorithm has, however, well known disadvantages. In this paper, we propose a new GC scheme called Partial Marking GC (PMGC) which is a valiant of generational GC. We implemented a Lisp interpreter with PMGC on a genera...

We consider the problem of interpolating scattered data in R 3 by an almost geometrically smooth GC 2 surface, where almost GC 2 means GC 2 except in a finite number of points (the vertices), where the surface is GC 1. A local method is proposed, based on employing so-called degenerate triangular Bernstein-B6zier patches. We give an analysis of quintic patches for GC I and patches of degree ele...

Kinase homology domain (KHD) phosphorylation is required for activation of guanylyl cyclase (GC)-A and -B. Phosphopeptide mapping identified multiple phosphorylation sites in GC-A and GC-B, but these approaches have difficulty identifying sites in poorly detected peptides. Here, a functional screen was conducted to identify novel sites. Conserved serines or threonines in the KHDs of phosphoryla...

Human transcription factor Sp1 contains three contiguous repeats of the C2H2-type zinc finger motif and binds to the decanucleotide sequence 5'-(G/T)GGGCGG(G/A)(G/A)(C/T)-3' (GC box). In order to determine whether the three-zinc finger peptide Sp1(530-623) has selectivity for sequence outside the GC box, we used a selection and amplification of binding experiment. The high affinity sequence gen...