Evolutionary accounts of morality consider behavior in rather simple scenarios. work on fairness focuses the division a windfall and, importantly, assumes that positions those involved are entirely symmetric. I more complicated strategic settings and find there is strong tendency for evolution to produce divisions consistent with so-called Nash bargaining solution. also uncover evolutionary imp...

duopoly game theory is applied to the wood industrial markets (sawnwood and pulpwood markets) in the north of iran. the nash equilibrium and the dynamic properties of the system based on marginal adjustments are determined. the probability that the nash equilibrium will be reached is almost zero. the dynamical properties of sawnwood and pulpwood prices derived via the duopoly game model are fou...

مکان‌یابی با درنظرگرفتن موضوع رقابت در بازار، یک تصمیم راهبردی و بلندمدت محسوب می­‌شود. چنانچه انتخاب مکان، بررسی‌­های لازم صورت نگیرد، حیات سازمان تحت تأثیر قرار می‌­گیرد. به‌­دلیل وجود پیچیدگی‌­های موجود مسائل مکان‌یابی، ارائه مدل‌های محدودیت­‌های متنوعی مواجه است. هدف این پژوهش، توسعه مدل رقابتی درنظر­گرفتن دو محصول از سوی سه رقیب است؛ برای منظور، مسئله به‌­صورت بازی مکان ـ قیمت تعریف استفاد...

background : non-alcoholic steatohepatitis (nash) is a common liver disease that, in the absence of treatment may progress to cirrhosis. there is a strong association of nash with insulin resistance; thus insulin sensitizer drugs have been used for this disease. the aim of this study was to compare the effect of pioglitazone with metformin on liver transaminases, the homa index, and adiponectin...

Let X be a variety over an algebraically closed field K . Its Nash blow-up is a variety over K with a projective morphism to X , which is an isomorphism over the smooth locus. Roughly speaking, it parametrizes all limits of tangent planes to X (a precise definition is given in §2 below). The Nash blow-up of a singular X is not always smooth but seems, in some sense, to be less singular than X ....

Recent studies indicate that metabolic oxidative stress, autophagy, and inflammation are hallmarks of nonalcoholic steatohepatitis (NASH) progression. However, the molecular mechanisms that link these important events in NASH remain unclear. In this study, we investigated the mechanistic role of purinergic receptor X7 (P2X7) in modulating autophagy and resultant inflammation in NASH in response...

In game theory, Nash equilibrium (named after John Forbes Nash, who proposed it) is a solution concept of a game involving two or more players, in which each player is assumed to know the equilibrium strategies of the other players, and no player has anything to gain by changing only his own strategy unilaterally. If each player has chosen a strategy and no player can benefit by changing his or...

Docosahexaenoic acid (DHA) regulates the lipid metabolism and inflammation that is closely associated with oxidative stress. The present study investigated the effects of DHA on the development of nonalcoholic steatohepatitis (NASH). To induce fatty liver, rats were fed choline-deficient high-fat diets (CDHF). The rats were then divided into 4 groups treated over the subsequent 6 weeks as follo...

Atypical fibroblast growth factors (FGF) 21 and 19 play a central role in energy metabolism through the mediation of Klotho coreceptor. Contradictory findings are available about the association of FGF21 and FGF19 with nonalcoholic fatty liver disease (NAFLD) in humans. We investigated the association of serum FGF21, FGF19 and liver Klotho coreceptor with non-alcoholic steatohepatitis (NASH) an...

Nonalcoholic fatty liver disease (NAFLD) encompasses a clinicopathologic spectrum of diseases ranging from isolated hepatic steatosis to nonalcoholic steatohepatitis (NASH), the more aggressive form of fatty liver disease that may progress to cirrhosis and cirrhosis-related complications, including hepatocellular carcinoma. The prevalence of NAFLD, including NASH, is also increasing in parallel...