Importance As society is increasingly becoming more networked, researchers are beginning to explore how social media can be used to study person-to-person communication about health and health care use. Twitter is an online messaging platform used by more than 300 million people who have generated several billion Tweets, yet little work has focused on the potential applications of these data fo...

A mutant polyoma virus (TT340), which replicates in F9 embryonal carcinoma (EC) cells and contains 2500 base pairs (bp) of additional DNA located in the early noncoding region of the genome, was analyzed to determined the DNA origin of the mutant insertion. Two fragments, representing repeated units of the 2500-bp insert, were isolated from TT340, labeled, and hybridized to the parental wild-ty...

The pathogenic mechanisms responsible for inflammatory bowel disease, especially ulcerative colitis (UC), are poorly understood. As an animal model, the oral administration of dextran sulfate sodium (DSS) induces colitis, which exhibits several clinical and histological features similar to UC. However, the pathogenic factors responsible for DSS-induced colitis and above all, the intestinal micr...

The impact of pressure on the backbone (15) N, (1) H and (13) C chemical shifts in N-terminally acetylated α-synuclein has been evaluated over a pressure range 1-2500 bar. Even while the chemical shifts fall very close to random coil values, as expected for an intrinsically disordered protein, substantial deviations in the pressure dependence of the chemical shifts are seen relative to those in...

زمینه و هدف: خلق مثبت انعطاف‌پذیری شناختی از عوامل تقویت کننده خلاقیت شناخته‌ می‌شوند. مطالعه حاضر با این فرض که احتمالاً اثرگذاری بر موجب ارتقا می‌شود، مهم را در بازه سنی 8 تا 12 سال بررسی کرده است. روش پژوهش: جامعة پژوهش شامل کلیه دانش آموزان دختر ۱۲ ساله مناطق 4 ۸ شهر تهران بودند. جامعه 60 نفر دو گروه ۱۰ (76/0±80/8) (76/0±20/11) به نمونه‌گیری دسترس انتخاب شد. پس جایگذاری تصادفی افراد گروه‌های...