Natural products are known to be a continuous source of potential anti-cancer agents due their chemical and biological diversity. This study aimed evaluate the in vitro cytotoxic properties medicinal plants mechanisms action human malignant melanoma cells. The investigated effect extracts on cell cycle, caspase-3/7, apoptosis induction using Annexin V-FITC/PI staining, morphological changes lac...

Introduction Koa (Acacia koa) is currently the most important commercialized hardwood in Hawai'r's forests. A sustainable supply of koa will depend on reforestation with the best adapted seed sources and perhaps with vegetatively propagated cultivars having unique traits. At present, koa forests are in a serious state of decline, and improvement appears warranted if sustainable supply is to be ...

Plant shoot tips do not survive exposure to liquid nitrogen temperatures without cryoprotective treatments. Some cryoprotectant solutions, such as plant vitrification solution 2 (PVS2), dehydrate cells and decrease lethal ice formation, but the extent of dehydration and the effect on water freezing properties are not known. We examined the effect of a PVS2 cryoprotection protocol on the water c...