OECD principles of validation of Quantitative Structure - Activity Relationships (QSAR) models for legislative purposes are given and explained. Reasons of their origination and development, like system REACH, are described. A basic impulse has come from some OECD countries followed by all (almost) other countries of the world.

The Review is one of a series of country reports carried out under the OECD's Regulatory Reform Programme, in response to the 1997 mandate by OECD Ministers. This report on regulatory reform in electricity in Korea was principally prepared by Mr. Peter Fraser for the OECD.

BACKGROUND The perceived health status indicator included in the OECD Health Statistics suffers from severe methodological limitations related to data collection. Furthermore, this indicator is also included in the OECD's Better Life Index, thus distorting the total health score of some OECD countries, among them Israel. The purpose of this paper is to explore the erroneous use of OECD health d...

Motivation. Mobility of highly skilled workers has increased substantially since the 1990s. This increased mobility has a major impact on science and technology across the world (OECD, 2001; OECD, 2008) and is considered a central element in contemporary globalization (OECD, 2008; Docquier & Rapoport, 2012). The mobility of human capital is particularly important not only for the explicit shari...

Numerous advancements in machinery performance on row-crop agricultural tractors have been made in recent years. Currently, the Organisation for Economic Co-operation and Development (OECD) only tests predetermined points (E.g., max. power, max. torque) for drawbar and hydraulic power. This method of testing has been used for many years with the tractor at a steady state which is usually not ty...

The OECD is a unique forum where the governments of 33 democracies work together to address the economic, social and environmental challenges of globalisation. The OECD is also at the forefront of efforts to understand and to help governments respond to new developments and concerns, such as corporate governance, the information economy and the challenges of an ageing population. The Organisati...

Although CVD mortality is 292 per 100 000 population, still lower than the OECD average of 299 (Figure 1), potential years of life lost, a commonly used measure of premature mortality, at 728 per 100 000 population for diseases of the circulatory system in 2011, is 25% higher than the OECD average of 581 (by using the age limit of 70), suggesting that CVD-related deaths occur earlier in life th...

During the austral summer of 1980-1981, a study was undertaken on the applicability of the Vollenweider-Organization for Economic Cooperation and Development (OECD) phosphorus loadingeutrophication response relationships to Lake Vanda, a permanently ice-covered, meromictic lake located in the Wright Valley of Antarctica. The Vollenweider-OECD empirical relationships had been developed on the ba...

Non-clinical animal studies to assess the safety of compounds under development have to comply with Good Laboratory Practice (GLP). The Organization for Economic Co-operation and Development (OECD) has established the Mutual Acceptance of Data (MAD) system in OECD member countries for the mutual acceptance of non-clinical safety study data. Since 1997 non-OECD-member countries have also been ab...

OBJECTIVE To review and update the conceptual framework, indicator content and research priorities of the Organisation for Economic Cooperation and Development's (OECD) Health Care Quality Indicators (HCQI) project, after a decade of collaborative work. DESIGN A structured assessment was carried out using a modified Delphi approach, followed by a consensus meeting, to assess the suite of HCQI...