PIR-A and PIR-B, paired immunoglobulin-like receptors encoded, respectively, by multiple Pira genes and a single Pirb gene in mice, are relatives of the human natural killer (NK) and Fc receptors. Monoclonal and polyclonal antibodies produced against a recombinant PIR protein identified cell surface glycoproteins of approximately 85 and approximately 120 kD on B cells, granulocytes, and macroph...

In malaria, development of resistance towards artemisinin derivatives has urged the need for new drugs or new drug combinations to tackle the drug resistant malaria. We studied the fresh root extract of Vetiver zizanioides (Linn.) Nash (VET) with a CDRI-CIMAP antimalarial α/β arteether (ART) together for their antimalarial potential. Our results showed additive to synergistic antimalarial activ...

It is believed that most giant elliptical galaxies possess nuclear black holes with masses in excess of 10 M⊙. Bondi accretion from the interstellar medium might then be expected to produce quasar-like luminosities from the nuclei of even quiescent elliptical galaxies. It is a puzzle that such luminosities are not observed. Motivated by this problem, Fabian & Rees have recently suggested that t...

Large organizations must be able to communicate with external suppliers, partners, and customers. Implementation of bidirectional E-mail and file transfers, however, may pose a significant security threat to the organization's internal systems. This article describes a network architecture for securing external communications that has been successfully implemented at Lockheed Missiles and Space...

We report on aetiological factors, clinical findings and prognosis of 87 patients with erythromelalgia (EM). This is the largest material reported in the western literature. There is a 100% follow up of patients with observation period up to 11 years. There were 61 females and 26 males. About two-thirds of the patients were primary cases and around three-quarters had a chronic condition. The co...

English): The identification of a murderer and the eventual conviction was largely due to forensic dentistry and in particular the use of bite marks on the victim compared with casts of the teeth of the accused. The Bundy case has become notorious in American legal circles. MeSH: Bites, Human -history (major); Forensic Dentistry -history; History, 20th Century; Homicide -history (major); Humans...

The X-ray data obtained with XMM-Newton is used to investigate the complex structure of the gas in the atmosphere of the Virgo cluster around M87. We construct a simple model for the temperature and density distribution. This model implies that the cumulative mass of the cluster gas is a power-law of its entropy index, kT n−2/3, similar to the Hydra cluster. This supports the idea that such pow...

Based on a detailed study of the temperature structure of the intracluster medium in the halo of M 87, abundance profiles of 7 elements, O, Mg, Si, S, Ar, Ca, and Fe are derived. In addition, abundance ratios are derived from the ratios of line strengths, whose temperature dependences are small within the temperature range of the ICM of M 87. The abundances of Si, S, Ar, Ca and Fe show strong d...

History has had its periods of magnificent excess, when vast amounts of human effort were devoted to cultural projects that transcended the necessities of survival and commerce. Obvious examples begin with the construction of the great pyramids. Much later, Europe's cathedrals were the ultimate commitment of society's surplus energy to expressions of the spirit. The explorations of the remote r...