If X is a metric space then CX and LX denote the semigroups of continuous and Lipschitz mappings, respectively, from X to itself. The relative rank of CX modulo LX is the least cardinality of any set U \LX where U generates CX . For a large class of separable metric spaces X we prove that the relative rank of CX modulo LX is uncountable. When X is the Baire space NN, this rank is א1. A large pa...

A seven French extra back-up catheter was placed in the ostium of the left coronary artery. Three guidewires were advanced: one in the LAD artery and the other two in the CX artery and branches. While crossing the CX occlusion with the wire, the vessel opened spontaneously (Figure 4) and an image suggestive of thrombotic material was seen in the CX and the second obtuse marginal branch (Figure ...

The gap junctional protein (Durlej et al., 2011; Xu, et al., 2012; Shaker et al., 2012) ( connexin, Cx ) are present in the cells that is responsible to exchange information and substance, which was channel protein and was essential for cell proliferation, differentiation and body growth and development of Cx. The Cx function is complex, in many physiological and pathological processes are invo...

David A. Mitchell1*, Oscar F. von Meien2, Luiz Fernando L. Luz Jr.2 and Nadia Krieger3 Departamento de Bioquímica, Universidade Federal do Paraná, Cx. P. 19046, Curitiba 81531-990, Paraná, Brazil Departamento de Engenharia Química, Universidade Federal do Paraná, Cx. P. 19011, Curitiba 81531-990, Paraná, Brazil Departamento de Química, Universidade Federal do Paraná, Cx. P. 19081, Curitiba 8153...

CX(3)CR1 expression is associated with the commitment of CSF-1R(+) myeloid precursors to the macrophage/dendritic cell (DC) lineage. However, the relationship of the CSF-1R(+) CX(3)CR1(+) macrophage/DC precursor (MDP) with other DC precursors and the role of CX(3)CR1 in macrophage and DC development remain unclear. We show that MDPs give rise to conventional DCs (cDCs), plasmacytoid DCs (PDCs),...

• Proof: X is j G implies that V = uX is G with mean uμ and variance uΣu. Thus its characteristic function, CV (t) = e ituμe−t 2uTΣu/2. But CV (t) = E[e itV ] = E[e TX ]. If we set t = 1, then this is E[e TX ] which is equal to CX(u). Thus, CX(u) = CV (1) = e iuμe−u TΣu/2. • Proof (other side): we are given that the charac function ofX, CX(u) = E[eiuTX ] = e μe−u TΣu/2. Consider V = uX. Thus, C...

BACKGROUND Mosquitoes in the Culex pipiens complex are among the most medically important vectors for human disease worldwide and include major vectors for lymphatic filariasis and West Nile virus transmission. However, detailed genetic studies in the complex are limited by the number of genetic markers available. Here, we describe methods for the rapid and efficient identification and developm...

A literature analysis coupled with new entomological surveys conducted between 2009 and 2012 led to changes in the list of mosquito species present on the island of La Réunion. Using morphological criteria, Orthopodomyia arboricollis is replaced by Or. reunionensis. On the basis of morphometrical and genetic criteria, Culex univittatus is replaced by Cx. neavei. Cx. poicilipes, which was alread...

CK2 is a pleiotropic protein kinase, which regulates many survival pathways and plays a global anti-apoptotic function. It is highly expressed in tumor cells, and is presently considered a promising therapeutic target. Among the many inhibitors available for this kinase, the recently developed CX-4945 and CX-5011 have proved to be very potent, selective and effective in inducing cell death in t...