Background and Objective: Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. Oxidative stress is one of the involved factors in CRC onset and progression. Recent examinations have revealed antioxidant characteristics of vitamin D. Given the vital role of this vitamin in balancing free radicals and antioxidant capacity, in this study we intended to review the association bet...

background while colorectal cancer (crc) is one of the most preventable causes of cancer mortality, it is one of the leading causes of cancer death in canada where crc screening uptake is suboptimal. given the increased rate of mortality and morbidity among mental health patients, their condition could be a potential barrier to crc screening due to greater difficulties in adhering to behaviours...

هدف از این مطالعه بررسی اثر آب تهی شده دوتریم (DDW) در غلظت­های مشخص بر روی سلول­های 29HT- و 480SW- بود. رده­های سلولی محیط RPMI حاوی مختلف DDW به مدت 24، 48 72 ساعت کشت داده شدند سپس درصد بقای روش سنجش سمیت مبتنی برMTT تعیین شد. یافته­ها نقش توأم کاهش افزایش زمان تیمار را مهار رشد اثبات رساند. کم­ترین میزان برای طی با غلظت ppm 30 ترتیب 23% 37% دست آمد. جهت اثرات جانبی دوتریم، طبیعی 12C2C نیز ت...

BACKGROUND Diabetic patients have a higher risk factor for colorectal cancer (CRC) metastasis. Stearoyl-CoA desaturase 1 (SCD1), the main enzyme responsible for producing monounsaturated fatty acids(MUFA) from saturated fatty acids, is frequently deregulated in both diabetes and CRC. The function and mechanism of SCD1 in metastasis of CRC and its relevance to glucose remains largely unknown. ...

PURPOSE Colorectal cancer (CRC) is a frequent malignant tumor with high death rate and poor prognosis. Few reports have explored the association between CRC development and long non-coding (lnc) RNAs expression. This study focused on the important role of a novel lncRNA XIST in the development of CRC. METHODS To investigate the function of long lncRNA XIST in CRC, its expression level was mon...

The expression of miR-638 was found downregulated in colorectal carcinoma (CRC) in our previous study. However, the role of miR-638 in CRC remains unknown. The aim of this study was to determine the function and mechanism of miR-638 in CRC. Here, we verified that miR-638 was frequently downregulated in CRC tissues compared with corresponding noncancerous tissues (NCTs) in an expanded CRC cohort...

Kevin J. Boudreau HEC Paris Nicola Lacetera Case Western Reserve University Karim R. Lakhani Harvard Business School This paper presents econometric evidence of two independent effects of adding more competitors on innovation: 1) a competition effect whereby increasing rivalry shapes, and often decreases, incentives to expend effort and invest in innovation; and 2) a parallel search effect wher...

Background: Colorectal Cancer (CRC) is a serious health problem, and its early detection is crucial for treatment and reducing mortality. Beliefs related to colorectal cancer are an affecting factor in a person’s decision about the CRC Program. The current study aimed at assessing the knowledge, attitude, and practice of healthcare providers regarding colorectal cancer screening based on the He...

BACKGROUND AND AIMS CRABS CLAW (CRC) encodes a transcription factor of the YABBY family that plays important roles in carpel and nectary development in Arabidopsis thaliana. Combined evolutionary and developmental studies suggest an ancestor of the CRC gene to have controlled carpel development in the last common ancestor of the angiosperms. Roles for CRC orthologues in leaf development and car...