Myelodysplastic syndrome (MDS) represents a heterogeneous hematopoietic stem-cell disorder that results in abnormal cellular maturation and peripheral blood cytopenias. MDS is characterized by progressive bone marrow failure, which can lead to bleeding, infections, and complications secondary to anemia. Approximately 35% to 40% of patients diagnosed with MDS progress to acute myeloid leukemia (...

Early, low-risk International Prognostic Scoring System (IPSS) myelodysplastic syndrome (MDS) is a heterogeneous disorder where the molecular and cellular hematopoietic defects are poorly understood. To gain insight into this condition, we analyzed gene expression profiles of marrow CD34 progenitor cells from normal-karyotype, low-blast-count MDS patients, age-matched controls, and patients wit...

The purpose of this study was to explore cytokine expression patterns and cytogenetic abnormalities of mesenchymal stem cells (MSCs) from the bone marrow microenvironment of Chinese patients with myelodysplastic syndromes (MDS). Bone marrow samples were obtained from 30 cases of MDS (MDS group) and 30 healthy donors (control group). The expression pattern of cytokines was detected by customized...

Zhang Shi-Yi, Wang Yong-juan, Gao Yang, Wang Tao Corresponding author: Wang Yong-juan, E-mail: [email protected] Abstract: The 4 4  MDS matrix over 2 F is widely used in the design of block cipher's linear diffusion layers. However, considering the cost of a lightweight cipher's implementation, the sum of XOR operations of a MDS matrix usually plays the role of measure. During the research on t...

Knowledge of the blast phenotype in myelodysplastic syndrome (MDS) would be valuable, as in other malignancies, but remains sparse. This is mainly because MDS blasts are a minor population in clinical samples, making analysis difficult. Thus, for this blast phenotype study, we prepared blast-rich specimens (using a new density centrifugation reagent for harvesting blasts) from blood and marrow ...

BACKGROUND Myelodysplastic syndrome (MDS) is a heterogeneous disorder characterized clinically by the presence of cytopenia/s. Limited data are available about the morphological spectrum and cytogenetic profile of Indian MDS patients. The aim of the study was to ascertain the clinico-pathological, morphological and cytogenetic spectrum of Indian MDS patients. MATERIAL AND METHODS A retrospect...

For a linear [n, k, d] code, it is well known that d ≤ n−k+1 (see [12]), and when d = n−k+1, it is called the MDS code (maximum distance separable). For every n ≤ q + 1 there is an MDS [n, k, d] code for any given k and d satisfying d = n − k + 1. It is just the geometric codes on a rational curve (see [15]). There is a long-standing conjecture about the MDS linear codes that is called the main...

The Cryptographics Algorithms AES and Twofish guarantee a high diffusion with the use of fixed MDS matrices of size 4 × 4. In this article variations to the Cryptographics Algorithms AES and Twofish are made. They allow that the process of cipher decipher come true with MDS matrices selected randomly from an algorithm that obtaining an MDS matrix of set of all the MDS matrices possible. A new S...

Recently, Yaakobi et al. introduced codes for b-symbol read channels, where the read operation is performed as a consecutive sequence of b > 2 symbols. In this paper, we establish a Singleton-type bound on b-symbol codes. Codes meeting the Singleton-type bound are called maximum distance separable (MDS) codes, and they are optimal in the sense they attain the maximal minimum bdistance. Based on...