A phase resetting curve (PRC) measures the transient change in the phase of a neural oscillator subject to an external perturbation. The PRC encapsulates the dynamical response of a neural oscillator and, as a result, it is often used for predicting phase-locked modes in neural networks. While phase is a fundamental concept, it has multiple definitions that may lead to contradictory results. We...

Previous studies have shown that platelet concentrates used in conjunction with appropriate growth media enhance osteogenic differentiation of human mesenchymal stromal cells (hMSCs). However, their potential in inducing osteogenesis of hMSCs when cultured in serum free medium has not been explored. Furthermore, the resulting osteogenic molecular signatures of the hMSCs have not been compared t...

BACKGROUND The Prevention Research Centers Healthy Aging Research Network (PRC-HAN), funded by the Centers for Disease Control and Prevention's (CDC's) Healthy Aging program, was created in 2001 to help develop partnerships and create a research agenda that promotes healthy aging. The nine universities that participate in the network use their expertise in aging research to collaborate with the...

OBJECTIVE To evaluate the contribution of six polymorphisms to the platelet reactivity in patients with acute coronary syndrome (ACS) treated with clopidogrel. METHODS Cross-sectional study of 278 consecutive patients with ACS. Detailed clinical information for each patient was collected and genotypes (CYP2C9*2, CYP2C9*3, CYP2C19*2, CYP2C19*17, CYP3A4*1B, and PON1-Q192R) were evaluated with T...

BACKGROUND AND OBJECTIVES Low perceived control (PC) and overestimations of controllability have each been related to obsessive compulsive (OC) symptoms and behaviour. OC beliefs and symptoms are also associated with a discrepancy between low perceived control (PC) and a high desire for control (DC). The present study sought to examine the influence of components of PC, low control-related self...

OBJECTIVE Multiple therapeutic modalities exist for giant cell tumors (GCT) in the distal radius. The majority of GCTs are amenable to curettage, with the expanded lesions requiring a more radical approach. This case report examines the technique of managing a GCT that has extended beyond the boundaries of the cortex and into local tissues. The decision to use arthroplasty versus arthrodesis an...

26 We tested a novel hypothesis, generated from representational accounts of medial 27 temporal lobe (MTL) function, that the major white matter tracts converging on 28 perirhinal cortex (PrC) and hippocampus (HC) would be differentially involved in face 29 and scene perception, respectively. Diffusion tensor imaging was applied in healthy 30 participants alongside an odd-one-out paradigm sensi...

Cerebrovascular disease (CBVD) is very common in the People's Republic of China (PRC). In 8 of 12 large cities in the PRC, CBVD ranked first in frequency as a cause of death. The ratio fo aneurysms to arteriovenous malformations (AVMs) was 0.84-2:1, much lower than in the United States (6.5:1). Hypertensive intracerebral hemorrhage (HIH) is the commonest cause of mortality in patients with CBVD...

Modern parallel and distributed applications have a wide range of communication characteristics and performance requirements. This paper presents the Programmable Routing Controller (PRC), a custom ASIC that supports exible network policies to accommodate diverse application requirements. By dedicating a small programmable processor to each incoming link, the PRC can implement wormhole, virtual...