BACKGROUND Translating scientific evidence into daily practice is problematic. All kinds of intervention strategies, using educational and/or directive strategies, aimed at modifying behavior, have evolved, but have been found only partially successful. In this article the focus is on (computerized) decision support systems (DSSs). DSSs intervene in physicians' daily routine, as opposed to inte...

This study implements decision support systems (DSS) in a business simulation game. Fifty-Eight companies, consisting of about 300 senior graduate students participating in a business game, developed DSS and reported on the systems developed. We later evaluated a number of variables related to their DSS: use of systems, contribution of systems, and user satisfaction. Our findings validate the u...

This position paper presents, firstly, the evolution of decision support systems (DSS) and the challenges in teaching in the field of DSS. Secondly, the concepts of management process, decision support technology, self-service business intelligence (SSBI), business simulation games and literature search results on business games associated with DSS are presented. Lastly, we suggest a conceptual...

This paper presents DSS, a distributed storage system that can be shared across a wide area network. DSS offers an infrastructure for supporting block-level caching and sharing in large distributed computing environments. DSS makes it possible to treat any disk either local or remote in the same way. This allows us to pool storage over a wide area network to create virtual disks that can be use...

It has been hypothesized that soy isoflavones exhibit anti-oxidative and anti-inflammatory functions, however, the effects of soy isoflavones on inflammatory bowel diseases remain unknown. Therefore, the present study aimed to investigate the effect and underlying mechanism of dietary soy isoflavones on dextran sulfate sodium (DSS)-induced colitis. Mice were administered DSS and soy isoflavones...

Responses by peripheral blood leukocytes may contribute to the pathogenesis of dengue hemorrhagic fever (DHF). We used DNA microarrays to reveal transcriptional patterns in the blood of 14 adults with DHF. Acute DHF was defined by an abundance of transcripts from cell cycle- and endoplasmic reticulum (ER)-related genes, suggesting a proliferative response accompanied by ER stress. Transcript-ab...

Dextran sodium sulfate (DSS) is a widely used chemical model for inflammatory bowel disease (IBD). It is thought that imbalances in the T helper (Th) cell subsets contribute to IBD. Recent studies suggest that the acute DSS-colitis model is polarized toward a Th1/Th17 profile based on RT-PCR analysis of colonic tissues. In the current study we determined whether colonic Th cells from DSS-coliti...

Oral administration of the novel anti-inflammatory peptide RDP58 markedly reduced the severity of dextran sulphate sodium (DSS) colitis as determined by clinical and quantitative histological criteria. The architecture of the colonic epithelium in DSS treated mice receiving RDP58 remained relatively normal compared with that of control DSS treated animals. 5-Bromo-2'-deoxyuridine (BrdU) labelli...