Climate is a fundamental and independent variable for human existence, as well as a factor in shaping the physical landscape within which human societies dwell. The record of human activities in South America before the arrival of the Spanish in 1532 is rich in archaeological remains but the process of reconstructing it is hampered by the lack of deciphered written languages. Through excavation...

J.R. Castrejón-Pita, W.R.S. Baxter, J. Morgan, S. Temple, G.D. Martin, and I.M. Hutchings Inkjet Research Centre, University of Cambridge, 17 Charles Babbage Road, Cambridge, CB3 0FS, United Kingdom Inca Digital Printers Ltd, 515 Coldhams Lane, Cambridge, CB1 3JS, United Kingdom Domino Printing Sciences Plc, Bar Hill, Cambridge, CB23 8TU, United Kingdom and Templetech Ltd, 10 Cambridge Road, Im...

1 Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, RJ, Brazil 2Universidade Federal do Estado do Rio de Janeiro, UNIRIO, Rio de Janeiro, RJ, Brazil 3Division of Clinical Research, Instituto Nacional de Câncer – INCA, Rio de Janeiro, RJ, Brazil 4 Instituto de Medicina Social, Universidade do Estado do Rio de Janeiro, UERJ, Rio de Janeiro, RJ, Brazil

The partition region qsopAB of the Coxiella burnetii plasmid QpH1 was analyzed. Locus qsopA alone appears to fulfill the partitioning function; QsopA represses its own promoter 17-fold. Two partition-associated incompatibility sites were identified: incA in a 200-bp region covering the qsopA promoter and incB in the qsopB locus.

UNLABELLED Mobile genetic elements play a pivotal role in the adaptation of bacterial populations, allowing them to rapidly cope with hostile conditions, including the presence of antimicrobial compounds. IncA/C conjugative plasmids (ACPs) are efficient vehicles for dissemination of multidrug resistance genes in a broad range of pathogenic species of Enterobacteriaceae ACPs have sporadically be...

Salmonella enterica subsp. enterica serovar Typhimurium strain 33676 was isolated in Mexico City, Mexico, from a patient with a systemic infection, and its complete genome sequence was determined using PacBio single-molecule real-time technology. Strain 33676 harbors an IncF plasmid carrying the extended-spectrum cephalosporin gene blaCMY-2 and a multidrug resistance IncA/C plasmid.

The INCA (Integrated Nitrogen in Catchments) model was applied to the River Tweed in the Scottish Borders, a large-scale (4400km2), spatially heterogeneous catchment, draining a wide range of agricultural land-use types, and which contributes approximately 20% of UK river flows to the North Sea. The model was calibrated for the first four years’ data record (1994 to 1997) and tested over the fo...