نتایج جستجو برای: مدل m gam
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where x ∈ R denotes a sample and xj ∈ R denotes the j-th explanatory variable for each j ∈ [1, p] , {j ∈ N|1 ≤ j ≤ p}. This was first proposed by Hastie and Tibshirani (1987) and is known as a generalized additive model (GAM). In this paper, we call fj(·) a weight function and f(·) a GAM predictor. This not only includes linear predictors but also captures nonlinear relationships between explan...
Localization of mRNAs is currently thought to be partially responsible for molecular sorting to specific compartments within the cell. In mammalian cells the best-studied example is the beta-actin mRNA that is localized to the cell processes, and its localization is necessary in migratory responses of cells. It is reasonable to assume that mRNA localization within cells is coupled to transmembr...
Escherichia coli strains bearing plasmids expressing phage P22 anti-RecBCD functions abc1 and abc2 were tested for the presence of recBC-like phenotypes. Abc2 induces moderate sensitivity to UV light in wild-type and recD mutant strains but severely sensitizes both recF and recJ mutants. Abc1 has little effect on UV sensitivity in wild-type or recF or recJ mutant hosts but increases the sensiti...
Gallium is antiproliferative to many types of cancer, due primarily to its ability to act as a non-functional mimic of ferric iron (Fe(3+)). Because Fe(3+) is needed for ribonucleotide reductase activity--and thus DNA synthesis--gallium can inhibit DNA production and cell division. Diagnostic gallium scans have shown that hepatocellular carcinoma (HCC) is commonly avid for gallium. Furthermore,...
We report the identification and functional analysis of nine genes from Gram-positive and Gram-negative bacteria and their phages that are similar to lambda (lambda) bet or Escherichia coli recT. Beta and RecT are single-strand DNA annealing proteins, referred to here as recombinases. Each of the nine other genes when expressed in E. coli carries out oligonucleotide-mediated recombination. To o...
Generalized additive models (GAMs) are a generalization of generalized linear models (GLMs) and constitute a powerful technique which has successfully proven its ability to capture nonlinear relationships between explanatory variables and a response variable in many domains. In this paper, GAMs are proposed as base classifiers for ensemble learning. Three alternative ensemble strategies for bin...
In the Large Helical Device (LHD), a reversed magnetic shear (RS) configuration having non-monotonic rotational transform profile was formed by intense counter neutral beam (NB) current drive. In the RS configuration helical plasma, the reversed shear Alfvén eigenmode (RSAE) with n=1 toroidal mode number was identified together with energetic-ion-driven geodesic acoustic mode (GAM) with n=0. Te...
equivalently [Gar,VIII.2], the corona M(X) \ ι(X) is empty. (Here M(X) is the maximal ideal space of the algebra H∞(X) of bounded holomorphic functions on X and ι is the natural inclusion X ↪→ M(X).) If X does not satisfy the corona theorem then X may be said to have corona. Riemann surfaces known to satisfy the corona theorem include the unit disk [Car], bordered Riemann surfaces [All] [Sto], ...
Ascorbic Acid, D isulfides, Redox-Potential, ESR Electron spin resonance (EPR) spectra dem onstrate the form ation of a com plex betw een the ascorbate ion and disulfides such as oxidized g lutathione, cystine, gam m a globulin, bovine serum album in, 4-4 ' d ith iopyrid ine, and dithiobutyric acid. However, except in the case o f 4-4 ' dithiopyridine, ascorbic acid (AH2) is not capable o f red...
The generation of high intensity coherent radiation m the soft X-ray region from a free electron laser will require the FEL to operate in the high gam or collective instability regime. In this mode of operation, which does not require a cavity resonator, the radiation field grows exponentially along the undulator until nonlinear effects bring on saturation . We discuss the conditions that the e...
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