The nephrotoxic potential of amphotericin B (5 mg/kg per day intraperitoneally for 3 weeks) has been investigated in salt-depleted, normal-salt, and salt-loaded rats. In salt-depleted rats, amphotericin B decreased creatinine clearance linearly with time, with an 85% reduction by week 3. In contrast, in normal-salt rats creatinine clearance was decreased but to a lesser extent at week 2 and 3, ...

Bamboo salt is a traditional Korean baked solar salt, processed by packing the solar salt (sea salt) in bamboo tubes and heating several times at high temperatures. The anti-tumor activity of bamboo salt was investigated and compared to those of other salt’s samples. Though solar salt and purified salt exhibited high tumor weight, bamboo salt is associated with a lower weight of tumor. Bamboo s...

High salt intake is a major risk factor for hypertension and is associated with cardiovascular events. Most countries exhibit a traditionally high salt intake; thus, identification of an optimal strategy for salt reduction at the population level may have a major impact on public health. In this multicenter, random-order, double-blind observational and interventional study, subjects with a high...

We have previously shown that microinjection of monoclonal antibody to atrial natriuretic peptide (ANP) into the caudal nucleus tractus solitarii causes a pressor response in salt-sensitive spontaneously hypertensive rats (SHR) fed a basal (1%) salt diet, suggesting that endogenous ANP in this region may be involved in the centrally mediated regulation of blood pressure in this model. The prese...

امروزه ورود به حوزه مدیریت کیفیت برای سازمان‌ها از اهمیت ویژه‌­ای برخوردار است. مدل­های تعالی سازمانی ابزاری است که را در این مسیر رهنمون می­‌کند. بدین منظور، ازجمله شبکه بانکی کشور، رویکردهای گوناگونی سازمان خود راستای تحقق ارزش‌های مدل­‌های استقرار می­کنند؛ اما محدودیت منابع موجود قبیل هزینه، نیروی انسانی، فرهنگ و غیره، تمامی رویکردها میسر نمی‌­سازد؛ ازاین‌رو مسئله اصلی کدام بیشترین تأثیر ارت...

کاهش هزینه‏‌های مرتبط با موجودی از مهم‌ترین استراتژی‌‏های هر بنگاه اقتصادی برای بقا و سوددهی در شرایط رقابتی امروزی است. این راستا مدل‏‌های کلاسیک هزینه‏‌ها مطرح شده‌اند؛ اما کنار مزایای فراوان دارای فرضیه‌های محدودکننده‌ای هستند. پژوهش، یک زنجیره سه­‌سطحی لجستیکی شامل تولیدکننده، توزیع‌‏کننده خرده‏‌فروش نظر گرفته می‏‌شود مسئله بهینه‌سازی مدل توزیع‌کننده موردبررسی قرار می‏‌گیرد. موردنظر، توزیع‏...

a highly selective electrode for bromide ion based on aza pyrilium derivative as an excellentionophore is described.the sensor exhibits a good linear response with a slope of ( 60±1 ) mv per decadeover the concentration range of ( 1×10-3 – 9×10-6 m ) , and a detection limit of ( 3×10-6 m ) of bromideions .the electrode response is independent of ph in the range of(4.0 –9.5).selectivity coeffici...

this study was carried out to determine the effect of fermentation, hydrothermal treatment, soda (na2co3), and table salt (nacl) addition on the extent of phytase activity and phytate degradation in three iranian wheat cultivars, namely, mahdavi, ghods, and roshan. the samples were milled to three different extraction rates, i.e. whole, 85%, and 75% flours and three kinds of leavening procedure...

objective(s): auraptene, a monoterpene coumarin from citrus species, exhibits cardioprotective effects.in this study, the effects of auraptene administration were investigated on blood pressure of normotensive and desoxycorticosterone acetate (doca) salt induced hypertensive rats. materials and methods: five weeks administration of auraptene (2, 4, 8 and 16 mg/kg/day) and nifedipine (0.25, 0.5,...

abstract a 71-year-old male with a long history of diabetes and hypertension was admitted with mild azotemia and recurrent hyponatremia. he was diagnosed with a pituitary gland cystic tumor. on careful evaluation, his hyponatremia was found to be due to cerebral salt wasting. the patient made a full recovery following treatment for cerebral salt wasting.