Laser powder bed fusion (LPBF)-manufactured Sc-Zr-modified Al–Mg alloy (Scalmalloy) has a bimodal microstructure comprising coarse grains (CGs) in the hot melt pool area and ultrafine (UFGs) along boundaries (MPBs). Owing to these microstructural features, an increase MPBs can UFGs, leading enhanced mechanical properties. However, effects of LPBF process parameters, especially laser scan strate...

A child with many symptoms of trisomy 22 syndrome is described. The child showed a 46,XY/47,XY,+22 chromosome constitution. This is the first reported case of a trisome 22 phenotype with such a mosaic karyotype.

In this paper, the logarithmically complete monotonicity results of the functions [Γ(1 + x)]y/Γ(1 + xy) and Γ(1 + y)[Γ(1 + x)]y/Γ(1 + xy) are established.

It has been known for some years that apparently female patients are sometimes found to have an XY sex chromosome complement. Morris (1953) focused attention upon the syndrome of testicular feminization in which, despite the presence of XY sex chromosomes and testes, the phenotype and secondary sexual development are female. Harnden and Stewart (1959) applied the term pure gonadal dysgenesis to...

The chiral glass behaviour of the nearest-neighbour random-bond XY spin glass in four dimensions is studied by Monte Carlo simulations. A chiral glass transition at T cg = 0.90 ± 0.05 is found by a finite-size scaling analysis of the results. The associated chiral correlation-length exponent is estimated to be ν cg = 0.6 ± 0.1 and η cg ∼ 0.25. The values for the chiral critical temperature and ...

YY super-males have rarely been detected in nature and only been artificially created in some fish species including tilapia and yellow catfish (Pelteobagrusfulvidraco), which provides a promising model for testis development and spermatogenesis. In our previous study, significant differences in morphology and miRNA expression were detected between XY and YY testis of yellow catfish. Here, sole...

OBJECTIVE Ovotesticular disorder of sexual development (DSD) is an unusual form of DSD, characterized by the coexistence of testicular and ovarian tissue in the same individual. In a subset of patients, ovotesticular DSD is caused by 46,XX/46,XY chimerism or mosaicism. To date, only a few monogenetic causes are known to be associated with XX and XY ovotesticular DSD. DESIGN AND METHODS Clinic...

Histone macroH2A1.2 and the murine heterochromatin protein 1, HP1 beta, have both been implicated in meiotic sex chromosome inactivation (MSCI) and the formation of the XY-body in male meiosis. In order to get a closer insight into the function of histone macroH2A1.2 we have investigated the localisation of macroH2A1.2 in surface spread spermatocytes from normal male mice and in oocytes of XX a...

Objective: To investigate antenatal detection the chromosome abnormalities in high risk pregnancies and correlation between karyotype analysis and FISH (Fluorescent In Situ Hybridization). Method: Were analyzed cytogenetic results from a total of 594 cases between 2008-2009. Amniotic fluid karyotyping and FISH have been offered to pregnant women with genetic risk, using the standard method and ...

Background: Disorders of sex development (DSD) are a medical condition that affects the normal process of sexual  Various of the genes needed for gonad development have been identified by investigation of patients with disorders sex development (DSD).Phenotypes of patients with 46,XY DSD range from atonalism in female phenotype with complete external  genitalia to male phenotype with testicular...