Background and Purpose—No stroke scale has been validated as an outcome measure using data from a clinical trial demonstrating a positive therapeutic effect. Therefore, we proposed to use data from the National Institute of Neurological Disorders and Stroke (NINDS) tPA Stroke Trial to determine whether the National Institutes of Health Stroke Scale (NIHSS) was valid in patients treated with tis...

Background and Purpose—Clot dissolution with tissue plasminogen activator (tPA) can lead to early clinical recovery after stroke. Transcranial Doppler (TCD) with low MHz frequency can determine arterial occlusion and monitor recanalization and may potentiate thrombolysis. Methods—Stroke patients receiving intravenous tPA were monitored during infusion with portable TCD (Multigon 500M; DWL Multi...

Introduction. Stroke is a type of nervous focal disorder that occurs suddenly because of acute vascular events. 113-149 out of 100000 persons (0.113-0.149%) face with stroke in Iran annually. This causes treatment costs and many disabilities. Recently, studies indicated that statins, as a class of drugs, could decrease the chance of stroke recurrence and probably disabilities after stroke onset...

Intravenous recombinant tissue-type plasminogen activator (rt-PA) therapy is highly recommended to patients who are diagnosed with ischemic stroke within 4.5 hours after the onset while mechanical clot retrieval can be attempted in patients who are not indicated for or cannot effectively receive intravenous rt-PA therapy. In this article, we report early treatment outcomes and discuss the usefu...

BACKGROUND AND PURPOSE The 15-item National Institutes of Health Stroke Scale (NIHSS) has been critiqued for its complexity and variability, and shortened versions have been proposed. This study aimed to compare the measurement properties of the original version with 3 shortened versions with 11, 8, and 5 items, respectively. METHODS Analyses were performed using data from an international, d...

BACKGROUND AND PURPOSE Some stroke patients and their families express reservations about participating in trials of experimental therapies for acute stroke. Among many reasons given for this is the concern that by participating, patients may be deprived of some component of routine care. We sought to determine the effect on outcome of participating in a clinical stroke trial while being treate...

Akut iskemik inmede ilk 4,5 saat içinde uygulanan rekombinan doku plazminojen aktivatörü (rt-PA) etkinliği kanıtlanmış bir tedavi yöntemidir. Bu çalışmada 01.01.2018 - 01.12.2021 tarihleri arasında trombolitik 71 akut inme hastasının verilerini analiz etmeyi ve merkezimizin deneyimlerini paylaşmayı amaçladık. Hastaların nörolojik durumları Ulusal Sağlık Enstitüleri İnme Skalası (NIHSS), engelli...

A 46-year-old womanwas admitted to the emergency department with a severe left hemispheric syndrome (NIH Stroke Scale [NIHSS] 11). CT showed an occlusion of the left middle cerebral artery, reaching from the distal main trunk (M1) to the inferior division (M2) (figure 1). IV thrombolysis was started and mechanical thrombectomy performed successfully. Postinterventional clinical examination show...

BACKGROUND AND PURPOSE Only a small percentage of stroke patients are treated with thrombolytic therapy. We sought to determine whether vessel occlusion in mild strokes represented a new target population for interventional therapy. METHODS We imaged 106 acute stroke patients with MRI. Patients were identified with evidence of middle cerebral artery (MCA) occlusion and mild or no stroke signs...

ObjectivesTo explore factors from the acute phase, and after three 12 months, associated with level of self-reported physical activity months a minor ischemic stroke National Institutes Health Stroke Scale (NIHSS) score ? 3 in persons 70 years or younger.Materials methodIn this longitudinal cohort study patients were recruited consecutively two units. Activity measured sets questions addressing...