نتایج جستجو برای: موج برشی sg

تعداد نتایج: 22423  

Journal: :The Biochemical journal 2007
Tiago Braga Mirjana Grujic Agneta Lukinius Lars Hellman Magnus Abrink Gunnar Pejler

SG (serglycin) PGs (proteoglycans) are strongly implicated in the assembly of MC (mast cell) granules. However, this notion has mainly been on the basis of studies of MCs of the connective tissue subtype, whereas the role of SG PG in mucosal MCs has not been explored. In the present study, we have addressed the latter issue by using mice with an inactivated SG gene. Bone marrow cells were diffe...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2008
Zahidul Islam Colleen C Hegg Hee Kyong Bae James J Pestka

Satratoxin G (SG) is a macrocyclic trichothecene mycotoxin produced by Stachybotrys chartarum, a mold suggested to play an etiologic role in damp building-related illnesses. Acute intranasal exposure of mice to SG specifically induces apoptosis in olfactory sensory neurons of the nose. The PC-12 rat pheochromocytoma cell model was used to elucidate potential mechanisms of SG-induced neuronal ce...

2013
Cristina Gareau Elise Houssin David Martel Laetitia Coudert Samia Mellaoui Marc-Etienne Huot Patrick Laprise Rachid Mazroui

The RNA-binding protein Fragile X Mental Retardation (FMRP) is an evolutionarily conserved protein that is particularly abundant in the brain due to its high expression in neurons. FMRP deficiency causes fragile X mental retardation syndrome. In neurons, FMRP controls the translation of target mRNAs in part by promoting dynamic transport in and out neuronal RNA granules. We and others have prev...

Journal: :Physiological genomics 2011
Hong Soon Kang Kyoko Okamoto Yukimasa Takeda Ju Youn Beak Kevin Gerrish Carl D Bortner Laura M DeGraff Taira Wada Wen Xie Anton M Jetten

Retinoid-related orphan receptor (ROR)α4 is the major RORα isoform expressed in adipose tissues and liver. In this study we demonstrate that RORα-deficient staggerer mice (RORα(sg/sg)) fed with a high-fat diet (HFD) exhibited reduced adiposity and hepatic triglyceride levels compared with wild-type (WT) littermates and were resistant to the development of hepatic steatosis, adipose-associated i...

ژورنال: فیزیک زمین و فضا 2016

مطالعه و مدلسازی ویژگی‌های سرعتی مناطق نزدیک سطح زمین به‌دلیل ارتباط مستقیم آن با تأسیسات شهری واقع برروی آن، از لحاظ ژئوتکنیکی و مهندسی زلزله از اهمیت خاصی برخوردار است. در سال‌های اخیر میکروترمور شکست مرزی (ReMi) برای تخمین منحنی‌های پاشش و در نهایت مدلسازی سرعت موج برشی، به-دلیل هزینه پائین و سرعت بالای برداشت داده‌ها مورد استقبال قرار گرفته است. اما مشکل اساسی در پردازش این داده‌ها وارون‌سا...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2011
Cuihong Jia Sutheera Sangsiri Bethany Belock Tania R Iqbal James J Pestka Colleen C Hegg

Intranasal aspiration of satratoxin G (SG), a mycotoxin produced by the black mold Stachybotrys chartarum, selectively induces apoptosis in olfactory sensory neurons (OSNs) in mouse olfactory epithelium (OE) through unknown mechanisms. Here, we show a dose-dependent induction of apoptosis 24 h post-SG exposure in vitro as measured by increased activated caspases in the OP6 olfactory placodal ce...

Journal: :Arquivos de neuro-psiquiatria 2005
Enio Alberto Comerlato Rosana Hermínia Scola Lineu César Werneck

The limb-girdle muscle dystrophy (LGMD) represents a heterogeneous group of muscular diseases with dominant and recessive inheritance, individualized by gene mutation. A group of 56 patients, 32 males and 24 females, with suggestive LGMD diagnosis were submitted to clinical evaluation, serum muscle enzymes, electromyography, muscle biopsy, and the immunoidentification (ID) of sarcoglycans (SG) ...

Journal: :Stem cell reports 2016
Martti Maimets Cecilia Rocchi Reinier Bron Sarah Pringle Jeroen Kuipers Ben N G Giepmans Robert G J Vries Hans Clevers Gerald de Haan Ronald van Os Robert P Coppes

Adult stem cells are the ultimate source for replenishment of salivary gland (SG) tissue. Self-renewal ability of stem cells is dependent on extrinsic niche signals that have not been unraveled for the SG. The ductal compartment in SG has been identified as the location harboring stem cells. Here, we report that rare SG ductal EpCAM(+) cells express nuclear β-catenin, indicating active Wnt sign...

2015
Anaïs Aulas Guillaume Caron Christos G. Gkogkas Nguyen-Vi Mohamed Laurie Destroismaisons Nahum Sonenberg Nicole Leclerc J. Alex Parker Christine Vande Velde

G3BP1, a target of TDP-43, is required for normal stress granule (SG) assembly, but the functional consequences of failed SG assembly remain unknown. Here, using both transformed cell lines and primary neurons, we investigated the functional impact of this disruption in SG dynamics. While stress-induced translational repression and recruitment of key SG proteins was undisturbed, depletion of G3...

ژورنال: :مهندسی مکانیک مدرس 2014
کامران دانشجو محمد رحیم زاده

در این مقاله به بررسی انتشار امواج الاستیک صفحه ای در مواد مرکب حاوی ذرات تقویت کننده نرم و سخت که بصورت تصادفی در محیط ماتریس توزیع شده اند می پردازیم. مدل تعمیم یافته خود سازگار دینامیکی که دقت مناسبی در مدلسازی درصد حجمی زیاد ذرات و نیز محدوده فرکانس بالا دارد، بدین منظور استفاده شد. پس از تشریح مدل، دو ماده مرکب حاوی ذرات نرم و سخت جهت بررسی انتخاب گردید. خواص انتشاری موج از قبیل سرعت فازی،...

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